阿育吠陀配方的植物化学评价及其抗氧化活性评价

IF 0.7 4区 化学 Q4 CHEMISTRY, ORGANIC Letters in Organic Chemistry Pub Date : 2023-11-28 DOI:10.2174/0115701786226175231023112257
Awadhesh Kumar, Akash Ved, Karuna S. shukla, Amit Kumar Nigam
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引用次数: 0

摘要

阿育吠陀配方的评价是非常广泛和深入的。该项目的目标是评估用于治疗消化系统疾病的阿育吠陀配方的植物化学和抗氧化活性。草药制剂通常是多种植物成分的单一或混合制剂,量化此类制剂中存在的标记物数量以确保产品的高质量至关重要。采用理化筛选、植物化学筛选、高效液相色谱法(HPTLC)对三种药材的提取物进行抗氧化活性测定。本研究对三种阿育吠陀配方(Sanjivini vati, Ajmodadi Churna和Avipattikar Churna)进行了理化研究。提取工艺测定了总酚和类黄酮的含量。采用三种方法计算所选配方的抗氧化能力;总抗氧化能力,铁还原能力和DPPH清除活性。采用HPTLC法分离有效成分。本研究表明,山茱萸、山茱萸和山茱萸是抗氧化成分的重要来源。采用HPTLC法分离有效成分。HPTLC技术显示了酚类和萜类物质的存在,这些物质负责抗氧化活性。酚类和萜类,由于其抗氧化活性,被用作消化系统疾病的重要来源。
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Phytochemical Evaluation of Selected Ayurvedic Formulations and Evaluate their Antioxidant Activity
: The Ayurvedic formulations' evaluation is very wide and deep. The project's goal was to evaluate the phytochemistry and antioxidant activity of Ayurvedic formulations used to treat digestive disorders. Herbal formulations are typically available as single or mixed formulations of multiple plant constituents, and it is critical to quantify the number of markers present in such formulations to ensure the product's high quality. The extract of formulations (Ajmodadi churna, Avipattikar churna, and Sanjivani vati) was subjected to physicochemical screening, phytochemical screening, HPTLC, and antioxidant activity was observed in the current study. Three ayurvedic formulations (Sanjivini vati, Ajmodadi Churna, and Avipattikar Churna) were studied physicochemically in this study. The extraction process determined the total phenolic and flavonoid content. The antioxidant capacity of the selected formulation was calculated by three methods; total antioxidant capacity, ferric-reducing power, and DPPH scavenging activity. The active constituent was isolated using the HPTLC method. This study shows that the formulations Ajmodai churna, Avipattikar churna, and Sanjivani vati are important sources of antioxidant compounds. The active constituent was isolated using the HPTLC method. The HPTLC technique showed the presence of phenolics and terpenoids that are responsible for antioxidant activity. Phenolics and Terpenoids, due to their antioxidant activity, are used as an important source for digestive disorders.
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来源期刊
Letters in Organic Chemistry
Letters in Organic Chemistry 化学-有机化学
CiteScore
1.30
自引率
12.50%
发文量
135
审稿时长
7 months
期刊介绍: Aims & Scope Letters in Organic Chemistry publishes original letters (short articles), research articles, mini-reviews and thematic issues based on mini-reviews and short articles, in all areas of organic chemistry including synthesis, bioorganic, medicinal, natural products, organometallic, supramolecular, molecular recognition and physical organic chemistry. The emphasis is to publish quality papers rapidly by taking full advantage of latest technology for both submission and review of the manuscripts. The journal is an essential reading for all organic chemists belonging to both academia and industry.
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