苯并噻唑试剂对羧酸的全氟烷基硫代氧化反应

IF 1.7 4区化学 Q3 CHEMISTRY, INORGANIC & NUCLEAR Journal of Fluorine Chemistry Pub Date : 2023-12-01 DOI:10.1016/j.jfluchem.2023.110231

Alex Haswell , Matteo Tironi , Haoyue Wang , Matthew N. Hopkinson

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引用次数: 0

摘要

利用一系列2-(全氟烷基硫代)苯并噻唑(BT-SRF)试剂作为全氟烷基硫代阴离子的方便来源，开发了易于获得的羧酸衍生物的全氟烷基硫代脱氧反应。该方法避免了底物的预活化，并提供了很少报道的具有SRF基团高达C6F13的全氟烷基硫酯。用五氟乙基硫化试剂BT-SC2F5对羧酸底物的调查也揭示了该方法作为一种获取未开发的氟化化合物的方法的通用性。

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Deoxygenative perfluoroalkylthiolation of carboxylic acids with benzothiazolium reagents

Deoxygenative perfluoroalkylthiolation reactions of readily available carboxylic acid derivatives have been developed using a series of 2-(perfluoroalkylthio)benzothiazolium (BT-SR_F) reagents as convenient sources of perfluoroalkylthiolate anions. This method avoids pre-activation of the substrates and delivers rarely reported perfluoroalkyl thioesters featuring SR_F groups up to C₆F₁₃. A survey of carboxylic acid substrates with the pentafluoroethylthiolating reagent BT-SC₂F₅ also revealed the generality of the approach as a method for accessing underexplored fluorinated compounds.

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来源期刊

Journal of Fluorine Chemistry 化学-无机化学与核化学

CiteScore

3.80

自引率

10.50%

发文量

审稿时长

33 days

期刊介绍： The Journal of Fluorine Chemistry contains reviews, original papers and short communications. The journal covers all aspects of pure and applied research on the chemistry as well as on the applications of fluorine, and of compounds or materials where fluorine exercises significant effects. This can include all chemistry research areas (inorganic, organic, organometallic, macromolecular and physical chemistry) but also includes papers on biological/biochemical related aspects of Fluorine chemistry as well as medicinal, agrochemical and pharmacological research. The Journal of Fluorine Chemistry also publishes environmental and industrial papers dealing with aspects of Fluorine chemistry on energy and material sciences. Preparative and physico-chemical investigations as well as theoretical, structural and mechanistic aspects are covered. The Journal, however, does not accept work of purely routine nature. For reviews and special issues on particular topics of fluorine chemistry or from selected symposia, please contact the Regional Editors for further details.