{"title":"含磺酰胺分子的艾滋病毒和结核分枝杆菌抑制剂的研究进展","authors":"Christiana Abimbola Salubi","doi":"10.1155/2023/3601764","DOIUrl":null,"url":null,"abstract":"Numerous studies have reported significant results regarding the efficacy of sulfonamides against <i>Mycobacterium tuberculosis</i> and various HIV strains. This scientific paper provides an overview of the progress made over a decade of sulfonamides against HIV-1 and mycobacteria and its development against extremely drug-resistant (XDR) and multidrug-resistant strains. The reviewed study offers novel insights into the structural design and structure-activity relationship (SAR) of sulfonamides that are effective and less toxic in combating HIV, <i>Mycobacterium tuberculosis</i>, and multidrug resistance.","PeriodicalId":15348,"journal":{"name":"Journal of Chemistry","volume":"20 1","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Research Progress in HIV and Mycobacterium tuberculosis Inhibitors Containing Sulfonamide Moiety\",\"authors\":\"Christiana Abimbola Salubi\",\"doi\":\"10.1155/2023/3601764\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Numerous studies have reported significant results regarding the efficacy of sulfonamides against <i>Mycobacterium tuberculosis</i> and various HIV strains. This scientific paper provides an overview of the progress made over a decade of sulfonamides against HIV-1 and mycobacteria and its development against extremely drug-resistant (XDR) and multidrug-resistant strains. The reviewed study offers novel insights into the structural design and structure-activity relationship (SAR) of sulfonamides that are effective and less toxic in combating HIV, <i>Mycobacterium tuberculosis</i>, and multidrug resistance.\",\"PeriodicalId\":15348,\"journal\":{\"name\":\"Journal of Chemistry\",\"volume\":\"20 1\",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2023-12-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1155/2023/3601764\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1155/2023/3601764","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Research Progress in HIV and Mycobacterium tuberculosis Inhibitors Containing Sulfonamide Moiety
Numerous studies have reported significant results regarding the efficacy of sulfonamides against Mycobacterium tuberculosis and various HIV strains. This scientific paper provides an overview of the progress made over a decade of sulfonamides against HIV-1 and mycobacteria and its development against extremely drug-resistant (XDR) and multidrug-resistant strains. The reviewed study offers novel insights into the structural design and structure-activity relationship (SAR) of sulfonamides that are effective and less toxic in combating HIV, Mycobacterium tuberculosis, and multidrug resistance.
期刊介绍：
Journal of Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry.
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