关注老年甲状腺癌患者

R. Lauretta, Marta Bianchini, M. Mormando, G. Puliani, M. Appetecchia
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摘要

由于与年龄、组织类型和诊断时的晚期相关的生物学原因,甲状腺癌在老年患者中更具侵袭性。在老年人中,甲状腺癌的诊断和治疗都会影响生活质量。本综述旨在收集和讨论老年甲状腺癌患者的不同治疗方法。我们的分析根据年龄检查了治疗性手术方法,以及这如何影响甲状腺癌患者的预后,以及碘131治疗的耐受性和有效性。此外,我们还研究了左甲状腺素抑制治疗对老年甲状腺癌患者是否总是必要和安全的,以及老年人全身治疗的安全性和有效性。我们还打算确定老年人甲状腺癌的特殊特征,并评估疾病及其治疗如何影响他们的生活质量。
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Focus on Thyroid Cancer in Elderly Patients
Thyroid cancer is more aggressive in elderly patients due to biological causes related to age, histotype, and the advanced stage at diagnosis. In the elderly, both the diagnosis and treatment of thyroid cancer impact quality of life. This review aimed to collect and discuss the different therapeutic approaches in elderly patients affected by thyroid cancer. Our analysis examined the therapeutic surgical approach according to age and how this affects the prognosis of patients with thyroid cancer, along with how iodine 131 therapy is tolerated and how effective it is. Furthermore, we investigated whether levothyroxine suppressive therapy is always necessary and safe in elderly patients with thyroid cancer and the safety and efficacy of systemic therapy in the elderly. We also intended to identify peculiar features of thyroid cancer in elderly subjects and to evaluate how the disease and its treatment affect their quality of life.
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