一名患有镰状细胞病的年轻女性体内的脆弱拟杆菌急性血源性骨髓炎

IF 1 Q4 INFECTIOUS DISEASES Case Reports in Infectious Diseases Pub Date : 2023-12-05 DOI:10.1155/2023/6340222
Nada Bassam Hamieh, Hiba Abdul Hamid Abou Layla, Rola Ali Ali, Zeina Bayram, Abdul Rahman Bizri
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引用次数: 0

摘要

镰状细胞病患者发生包括骨髓炎在内的多种感染的风险增加。报告最多的致病菌是沙门氏菌和金黄色葡萄球菌。包括脆弱拟杆菌在内的厌氧感染并不常见。在此,我们报告一例28岁女性镰状细胞病合并急性血源性脆弱拟杆菌性胫骨骨髓炎的病例。诊断是通过从血液和胫骨液培养中分离出生物体。患者成功地进行了一个疗程的静脉注射,随后口服抗生素和经皮引流收集,反应良好。本病例报告将阐明脆弱拟杆菌作为镰状细胞病患者骨髓炎的致病生物的重要性,从而影响这些患者的管理。
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Bacteroides fragilis Acute Hematogenous Osteomyelitis in a Young Female with Sickle Cell Disease
Patients with sickle cell disease are at increased risk for multiple infections including osteomyelitis. The most reported causative organisms are Salmonella spp. and Staphylococcus aureus. Anaerobic infections including Bacteroides fragilis are not commonly seen. Here, we report the first case of a 28-year-old female patient with sickle cell disease and acute hematogenous Bacteroides fragilis tibial osteomyelitis. Diagnosis was made by isolating the organism from blood and tibial fluid cultures. The patient was successfully managed with a course of intravenous followed by oral antibiotics and percutaneous drainage of collection and responded well. This case report will shed light on the importance of Bacteroides fragilis as a causative organism for osteomyelitis in sickle cell disease patients, thereby affecting the management of these patients.
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审稿时长
13 weeks
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