新皮层神经元的适应和爆发可能是由一个快速钾电导控制的。

Quarterly journal of experimental physiology (Cambridge, England) Pub Date : 1989-03-01 DOI:10.1113/expphysiol.1989.sp003260

N J Berman, P C Bush, R J Douglas

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引用次数: 10

摘要

我们使用计算机模拟模型神经元和体外细胞内记录来证明，新皮质神经元对重复放电的适应可以用快速钾电流来解释，而快速钾电流的失活被细胞内钙延缓。该电流的最大振幅决定了神经元是以常规模式放电还是以突发模式放电。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Adaptation and bursting in neocortical neurones may be controlled by a single fast potassium conductance.

We have used computer simulation of a model neurone and in vitro intracellular recording to demonstrate that the adaptation of repetitive discharge in neocortical neurones can be explained by a fast potassium current whose inactivation is retarded by intracellular calcium. The maximum amplitude of this current determines whether the neurone will discharge in regular or burst mode.

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Quarterly journal of experimental physiology (Cambridge, England)

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