用于预测雌激素受体阳性、人类表皮生长因子受体 2 阴性和结节阳性乳腺癌患者基因表达检测高危人群的简化风险评分系统。

IF 1.2 4区医学 Q3 SURGERY Annals of Surgical Treatment and Research Pub Date : 2023-11-29 DOI:10.4174/astr.2023.105.6.360

Kwang Hyun Yoon, Suk Jun Lee, Yujin Kim, Jee Hyun Ahn, Jee Ye Kim, Hyung Seok Park, Seung Il Kim, Seho Park

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引用次数: 0

摘要

基因表达检验（GET）用于预测化疗反应和复发风险。一些随机临床试验表明，即使不进行辅助化疗，一些结节阳性患者也能获得良好的生存结果。本研究旨在利用传统的临床病理因素预测 Oncotype DX（Genomic Health）和 MammaPrint（Agendia）的结果。

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A simplified risk scoring system for predicting high-risk groups in gene expression tests for patients with estrogen receptor-positive, human epidermal growth factor receptor 2-negative, and node-positive breast cancer.

The gene expression test (GET) was used to predict the response to chemotherapy and the recurrence risk. Several randomized clinical trials have demonstrated that some patients with node-positive disease can achieve favorable survival outcomes even without adjuvant chemotherapy. This study aimed to predict the results of Oncotype DX (Genomic Health) and MammaPrint (Agendia) using traditional clinicopathological factors.

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来源期刊

Annals of Surgical Treatment and Research SURGERY-

CiteScore

2.30

自引率

7.10%

发文量

期刊介绍： Manuscripts to the Annals of Surgical Treatment and Research (Ann Surg Treat Res) should be written in English according to the instructions for authors. If the details are not described below, the style should follow the Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writing and Editing for Biomedical Publications available at International Committee of Medical Journal Editors (ICMJE) website (http://www.icmje.org).