Ogochukwu Kelechi Onyeso, Arinze Kingsley Ugwu, Henrietha Chibuzor Adandom, Suha Damag, Kelechi Mirabel Onyeso, James Okechukwu Abugu, Okwukweka Emmanuela Aruma, Adesola Christiana Odole, Oluwaghohunmi A. Awosoga, Charles Ikechukwu Ezema
{"title":"焊接职业对血清铝水平的影响及其与身体健康、认知功能和生活质量的关系：一项横断面研究","authors":"Ogochukwu Kelechi Onyeso, Arinze Kingsley Ugwu, Henrietha Chibuzor Adandom, Suha Damag, Kelechi Mirabel Onyeso, James Okechukwu Abugu, Okwukweka Emmanuela Aruma, Adesola Christiana Odole, Oluwaghohunmi A. Awosoga, Charles Ikechukwu Ezema","doi":"10.1007/s00420-023-02038-8","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objective</h3><p>There is an occupational health concern about welders’ inhalation of toxic aluminium fumes. We investigated whether serum aluminium level (SAL) and demographic variables can significantly predict physical health parameters, cognition, and quality of life (QoL) among welders.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>The cross-sectional study involved 100 age- and location-matched men (50 welders and 50 non-welders). SAL obtained using a graphite furnace atomic absorption spectrometer, and data collected using blood pressure and body mass index (BMI) apparatuses, biodata form, pain rating scale, General Practitioner Assessment of Cognition, WHOQoL-BREF, and Nordic musculoskeletal symptoms (MSS) questionnaire were analysed using independent samples t test, chi-square, Pearson’s correlation, and hierarchical linear regression.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Welders had significantly higher SAL (mean difference [MD] = 1.77 µg/L, <i>p</i> < 0.001), lower QoL (MD = 3.92, <i>p</i> = 0.039), and higher prevalence of MSS on the neck (<i>χ</i><sup>2</sup> = 10.187, <i>p</i> = 0.001), shoulder (<i>χ</i><sup>2</sup> = 9.007, <i>p</i> = 0.003), upper back (<i>χ</i><sup>2</sup> = 6.832, <i>p</i> = 0.009), and knee (<i>χ</i><sup>2</sup> = 12.190, <i>p</i> < 0.001) than non-welders. There was a significant bivariate association between SAL, systolic blood pressure (β = 0.313, <i>p</i> = 0.002), and BMI (β = 0.279, <i>p</i> = 0.005), but not pain intensity, cognition, or QoL. SAL remained a significant predictor of systolic blood pressure after adjustment for physical health and QoL parameters (β = 0.191, <i>p</i> = 0.044). The association between SAL and social QoL became significant after adjustment for physical health and other QoL domains (β = − 0.210, <i>p</i> = 0.032) and demographic variables (β = − 0.233, <i>p</i> = 0.046).</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Welders had significantly higher SAL, musculoskeletal symptoms, blood pressure, and lower QoL than non-welders. SAL was associated with adverse physical health parameters and social-related QoL, not cognition. We recommend routine aluminium bioavailability and physical health checks among welders.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"31 1","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of welding occupation on serum aluminium level and its association with physical health, cognitive function, and quality of life: a cross-sectional study\",\"authors\":\"Ogochukwu Kelechi Onyeso, Arinze Kingsley Ugwu, Henrietha Chibuzor Adandom, Suha Damag, Kelechi Mirabel Onyeso, James Okechukwu Abugu, Okwukweka Emmanuela Aruma, Adesola Christiana Odole, Oluwaghohunmi A. Awosoga, Charles Ikechukwu Ezema\",\"doi\":\"10.1007/s00420-023-02038-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<h3 data-test=\\\"abstract-sub-heading\\\">Objective</h3><p>There is an occupational health concern about welders’ inhalation of toxic aluminium fumes. We investigated whether serum aluminium level (SAL) and demographic variables can significantly predict physical health parameters, cognition, and quality of life (QoL) among welders.</p><h3 data-test=\\\"abstract-sub-heading\\\">Methods</h3><p>The cross-sectional study involved 100 age- and location-matched men (50 welders and 50 non-welders). SAL obtained using a graphite furnace atomic absorption spectrometer, and data collected using blood pressure and body mass index (BMI) apparatuses, biodata form, pain rating scale, General Practitioner Assessment of Cognition, WHOQoL-BREF, and Nordic musculoskeletal symptoms (MSS) questionnaire were analysed using independent samples t test, chi-square, Pearson’s correlation, and hierarchical linear regression.</p><h3 data-test=\\\"abstract-sub-heading\\\">Results</h3><p>Welders had significantly higher SAL (mean difference [MD] = 1.77 µg/L, <i>p</i> < 0.001), lower QoL (MD = 3.92, <i>p</i> = 0.039), and higher prevalence of MSS on the neck (<i>χ</i><sup>2</sup> = 10.187, <i>p</i> = 0.001), shoulder (<i>χ</i><sup>2</sup> = 9.007, <i>p</i> = 0.003), upper back (<i>χ</i><sup>2</sup> = 6.832, <i>p</i> = 0.009), and knee (<i>χ</i><sup>2</sup> = 12.190, <i>p</i> < 0.001) than non-welders. There was a significant bivariate association between SAL, systolic blood pressure (β = 0.313, <i>p</i> = 0.002), and BMI (β = 0.279, <i>p</i> = 0.005), but not pain intensity, cognition, or QoL. SAL remained a significant predictor of systolic blood pressure after adjustment for physical health and QoL parameters (β = 0.191, <i>p</i> = 0.044). The association between SAL and social QoL became significant after adjustment for physical health and other QoL domains (β = − 0.210, <i>p</i> = 0.032) and demographic variables (β = − 0.233, <i>p</i> = 0.046).</p><h3 data-test=\\\"abstract-sub-heading\\\">Conclusion</h3><p>Welders had significantly higher SAL, musculoskeletal symptoms, blood pressure, and lower QoL than non-welders. SAL was associated with adverse physical health parameters and social-related QoL, not cognition. We recommend routine aluminium bioavailability and physical health checks among welders.</p>\",\"PeriodicalId\":13761,\"journal\":{\"name\":\"International Archives of Occupational and Environmental Health\",\"volume\":\"31 1\",\"pages\":\"\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2023-12-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Archives of Occupational and Environmental Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00420-023-02038-8\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Archives of Occupational and Environmental Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00420-023-02038-8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Impact of welding occupation on serum aluminium level and its association with physical health, cognitive function, and quality of life: a cross-sectional study
Objective
There is an occupational health concern about welders’ inhalation of toxic aluminium fumes. We investigated whether serum aluminium level (SAL) and demographic variables can significantly predict physical health parameters, cognition, and quality of life (QoL) among welders.
Methods
The cross-sectional study involved 100 age- and location-matched men (50 welders and 50 non-welders). SAL obtained using a graphite furnace atomic absorption spectrometer, and data collected using blood pressure and body mass index (BMI) apparatuses, biodata form, pain rating scale, General Practitioner Assessment of Cognition, WHOQoL-BREF, and Nordic musculoskeletal symptoms (MSS) questionnaire were analysed using independent samples t test, chi-square, Pearson’s correlation, and hierarchical linear regression.
Results
Welders had significantly higher SAL (mean difference [MD] = 1.77 µg/L, p < 0.001), lower QoL (MD = 3.92, p = 0.039), and higher prevalence of MSS on the neck (χ2 = 10.187, p = 0.001), shoulder (χ2 = 9.007, p = 0.003), upper back (χ2 = 6.832, p = 0.009), and knee (χ2 = 12.190, p < 0.001) than non-welders. There was a significant bivariate association between SAL, systolic blood pressure (β = 0.313, p = 0.002), and BMI (β = 0.279, p = 0.005), but not pain intensity, cognition, or QoL. SAL remained a significant predictor of systolic blood pressure after adjustment for physical health and QoL parameters (β = 0.191, p = 0.044). The association between SAL and social QoL became significant after adjustment for physical health and other QoL domains (β = − 0.210, p = 0.032) and demographic variables (β = − 0.233, p = 0.046).
Conclusion
Welders had significantly higher SAL, musculoskeletal symptoms, blood pressure, and lower QoL than non-welders. SAL was associated with adverse physical health parameters and social-related QoL, not cognition. We recommend routine aluminium bioavailability and physical health checks among welders.
期刊介绍：
International Archives of Occupational and Environmental Health publishes Editorials, Review Articles, Original Articles, and Letters to the Editor. It welcomes any manuscripts dealing with occupational or ambient environmental problems, with a special interest in research at the interface of occupational health and clinical medicine. The scope ranges from Biological Monitoring to Dermatology, from Fibers and Dust to Human Toxicology, from Nanomaterials and Ultra-fine Dust to Night- and Shift Work, from Psycho-mental Distress and Burnout to Vibrations. A complete list of topics can be found on the right-hand side under For authors and editors.
In addition, all papers should be based on present-day standards and relate to:
-Clinical and epidemiological studies on morbidity and mortality
-Clinical epidemiological studies on the parameters relevant to the estimation of health risks
-Human experimental studies on environmental health effects. Animal experiments are only acceptable if relevant to pathogenic aspects.
-Methods for studying the topics mentioned above.
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