铅中毒的胃肠道表现:简要报告。

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Iranian Journal of Medical Sciences Pub Date : 2023-11-01 DOI:10.30476/IJMS.2023.95824.2749
Masumeh Safaee, Mahdi Malekzadeh, Narges Motamedi, Masoud Sayadishahraki, Nastaran Eizadi-Mood
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引用次数: 0

摘要

铅中毒的胃肠道(GI)表现包括腹痛、便秘和腹泻。根据症状的严重程度,需要进行外科会诊。本研究旨在比较因铅中毒住院患者的平均血铅水平和各种 Gl 症状。这项回顾性横断面研究于 2020 年在中毒患者的主要地区转诊中心 Khorshid 医院(伊朗伊斯法罕)进行。研究共纳入了 2017-2018 年期间因铅中毒住院的 82 名年龄≥18 岁的患者。患者信息均从医院病历中提取,包括人口统计学信息、临床表现、血铅水平和治疗结果。患者的平均年龄为(48.18±11.9)岁,91.5%为男性,62.2%的患者有多种消化道症状,其中以腹痛为主(31.7%)。有多种消化道症状的患者血铅含量高于只有一种症状的患者(P=0.01)。14.6%的患者需要进行手术治疗。多种消化道症状是血铅水平超过 70 mg/dL 的主要预测因素(P=0.03,Odds ratio=3.06,95% CI=1.09-8.61)。鉴于腹痛的普遍性及其与血铅水平升高的关系,腹痛的鉴别诊断应包括铅中毒。
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Gastrointestinal Manifestations of Lead Poisoning: A Brief Report.

Gastrointestinal (GI) manifestations of lead poisoning include abdominal pain, constipation, and diarrhea. Depending on the severity of a symptom, surgical consultation is required. The present study aimed to make a comparison between the mean blood lead levels of patients hospitalized for lead toxicity and the various Gl symptoms. A retrospective cross-sectional study was performed in 2020 at Khorshid Hospital, the main regional referral center for poisoned patients (Isfahan, Iran). A total of 82 patients aged ≥18 years who were hospitalized for lead poisoning during 2017-2018 were included in the study. Patients' information was extracted from hospital medical records, including demographic information, clinical manifestations, blood lead levels, and treatment outcome. The mean age of the patients was 48.18±11.9 years, 91.5% were men, and 62.2% suffered from multiple GI symptoms, with abdominal pain being predominant (31.7%). Blood lead levels in patients with multiple GI symptoms were higher than those with only one symptom (P=0.01). Surgical consultation was required in 14.6% of the patients. Multiple GI symptoms were the main predictive factor for blood lead levels above 70 mg/dL (P=0.03, Odds ratio=3.06, 95% CI=1.09-8.61). Given the prevalence of abdominal pain and its association with elevated blood lead levels, differential diagnosis of abdominal pain should include lead toxicity.

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来源期刊
Iranian Journal of Medical Sciences
Iranian Journal of Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
3.20
自引率
0.00%
发文量
84
审稿时长
12 weeks
期刊介绍: The Iranian Journal of Medical Sciences (IJMS) is an international quarterly biomedical publication, which is sponsored by Shiraz University of Medical Sciences. The IJMS intends to provide a scientific medium of com­muni­cation for researchers throughout the globe. The journal welcomes original clinical articles as well as clinically oriented basic science re­search experiences on prevalent diseases in the region and analysis of various regional problems.
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