弗朗索瓦-格罗斯:从抗生素到信使核糖核酸。

Pub Date : 2024-03-29 DOI:10.5802/crbiol.130
Moshe Yaniv
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引用次数: 0

摘要

弗朗索瓦-格罗斯是法国著名的分子生物学家,1961 年对信使核糖核酸的发现做出了重大贡献。他在细菌 mRNA 及其翻译成蛋白质方面进行了杰出的研究,随后又在肌肉分化方面开展了开创性的工作。我有幸成为他的研究生之一,我在科学上的成功在很大程度上要归功于他。在这篇短文中,我将描述弗朗索瓦战后最初的研究如何引导他发现细菌中存在短效 RNA,即包含蛋白质合成信息的信使 RNA。我还将讲述他对他的学生以及他们在科学领域的载体所产生的影响。
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François Gros: from antibiotics to messenger RNA.

François Gros was a prominent French Molecular Biologist who made a major contribution to the discovery of messenger RNA in 1961. He pursued outstanding research on bacterial mRNA and its translation into proteins followed by pioneering work on muscle differentiation. I was lucky to be among his graduate students and owe much of my success in science to him. In this short text I will describe how the initial post-war studies of François guided him to discover the existence of short-lived RNA in bacteria, the messenger RNA containing the information for protein synthesis. I will also recount the influence he had on his students and their carrier in science.

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