关于 VIPoma 的所有知识:最新研究综述。

IF 3.2 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Presse Medicale Pub Date : 2023-12-16 DOI:10.1016/j.lpm.2023.104222
Emija Nikola Karele
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引用次数: 0

摘要

血管活性肠肽分泌瘤(VIP瘤)是一种罕见的恶性神经内分泌肿瘤,其特征是由于VIP的非调节性分泌增加而导致的水样腹泻、低钾血症和无水症。VIP 瘤的诊断依据是最常见的症状、血液和粪便的实验室分析、放射成像和免疫组化结果。主要治疗方法包括补充液体、纠正电解质平衡、使用体生长抑素类似物进行药物治疗、手术切除和化疗。本综述旨在介绍有关 VIPoma 流行病学、病理生理学、诊断和治疗的最新研究。
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All you need to know about VIPoma: Review on the latest studies

Vasoactive intestinal peptide secreting tumor (VIPoma) is a rare mostly malignant neuroendocrine tumor that is characterized by watery diarrhea, hypokalemia and achlorhydria due to the nonregulated increased secretion of VIP. VIPomas ar diagnosed by the presence of the most common symptoms, laboratory analysis of blood and stool, radiological imaging and immunohistochemical findings. Primary treatment includes fluid replacement, electrolyte balance correction, pharmacological treatment with somatostatin analogs, surgical resection and chemotherapy. This review aims to provide an insight into the latest research on VIPoma epidemiology, pathophysiology, diagnostics and treatment.

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来源期刊
Presse Medicale
Presse Medicale 医学-医学:内科
自引率
3.70%
发文量
40
审稿时长
43 days
期刊介绍: Seule revue médicale "généraliste" de haut niveau, La Presse Médicale est l''équivalent francophone des grandes revues anglosaxonnes de publication et de formation continue. A raison d''un numéro par mois, La Presse Médicale vous offre une double approche éditoriale : - des publications originales (articles originaux, revues systématiques, cas cliniques) soumises à double expertise, portant sur les avancées médicales les plus récentes ; - une partie orientée vers la FMC, vous propose une mise à jour permanente et de haut niveau de vos connaissances, sous forme de dossiers thématiques et de mises au point dans les principales spécialités médicales, pour vous aider à optimiser votre formation.
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