PSY-SIM 模型:利用真实世界的数据为慢性精神障碍患者的医疗保健政策提供信息。

IF 5.3 1区 医学 Q1 PSYCHIATRY Schizophrenia Bulletin Pub Date : 2024-08-27 DOI:10.1093/schbul/sbad175
Claire de Oliveira, Joyce Mason, Linda Luu, Tomisin Iwajomo, Frances Simbulan, Paul Kurdyak, Petros Pechlivanoglou
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引用次数: 0

摘要

背景与假设:慢性精神障碍是一种严重的致残性精神障碍,与不良的医疗和精神治疗效果以及高昂的医疗费用相关。这项工作的目的是为慢性精神病患者开发一个微观模拟模型,并利用该模型来研究戒烟措施对患者治疗效果的影响:研究设计:利用加拿大安大略省的健康记录和调查数据,开发了 PSY-SIM 模型来模拟慢性精神病患者的健康和成本结果。随后,该模型被用于研究安大略省的安大略省患者吸烟治疗(STOP)计划对慢性病发展、预期寿命、生活质量和终生医疗费用的影响:研究结果:患有慢性精神病的人一生中患充血性心力衰竭的风险为 63%,患呼吸系统疾病、癌症和糖尿病的风险约为 50%,预期寿命为 76 岁。该模型表明,STOP 计划可以降低发病率,提高生存率和生活质量,但医疗费用的增加幅度不大。在长期戒烟率为 4.4% 的情况下,与维持现状相比,STOP 计划的增量成本效益比为 41,936 美元/QALY:结论:在慢性精神障碍患者中开展戒烟活动具有成本效益。这些研究结果对决策者和临床医生改善这类患者的健康状况具有重要意义。
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The PSY-SIM Model: Using Real-World Data to Inform Health Care Policy for Individuals With Chronic Psychotic Disorders.

Background and hypothesis: Few microsimulation models have been developed for chronic psychotic disorders, severe and disabling mental disorders associated with poor medical and psychiatric outcomes, and high costs of care. The objective of this work was to develop a microsimulation model for individuals with chronic psychotic disorders and to use the model to examine the impact of a smoking cessation initiative on patient outcomes.

Study design: Using health records and survey data from Ontario, Canada, the PSY-SIM model was developed to simulate health and cost outcomes of individuals with chronic psychotic disorders. The model was then used to examine the impact of the Smoking Treatment for Ontario Patients (STOP) program from Ontario on the development of chronic conditions, life expectancy, quality of life, and lifetime health care costs.

Study results: Individuals with chronic psychotic disorders had a lifetime risk of 63% for congestive heart failure and roughly 50% for respiratory disease, cancer and diabetes, and a life expectancy of 76 years. The model suggests the STOP program can reduce morbidity and lead to survival and quality of life gains with modest increases in health care costs. At a long-term quit rate of 4.4%, the incremental cost-effectiveness ratio of the STOP program was $41,936/QALY compared with status quo.

Conclusions: Smoking cessation initiatives among individuals with chronic psychotic disorders can be cost-effective. These findings will be relevant for decision-makers and clinicians looking to improving health outcomes among this patient population.

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来源期刊
Schizophrenia Bulletin
Schizophrenia Bulletin 医学-精神病学
CiteScore
11.40
自引率
6.10%
发文量
163
审稿时长
4-8 weeks
期刊介绍: Schizophrenia Bulletin seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia. We view the field as broad and deep, and will publish new knowledge ranging from the molecular basis to social and cultural factors. We will give new emphasis to translational reports which simultaneously highlight basic neurobiological mechanisms and clinical manifestations. Some of the Bulletin content is invited as special features or manuscripts organized as a theme by special guest editors. Most pages of the Bulletin are devoted to unsolicited manuscripts of high quality that report original data or where we can provide a special venue for a major study or workshop report. Supplement issues are sometimes provided for manuscripts reporting from a recent conference.
期刊最新文献
Non-psychotic Outcomes in Young People at Ultra-High Risk of Developing a Psychotic Disorder: A Long-Term Follow-up Study. Network Localization of State and Trait of Auditory Verbal Hallucinations in Schizophrenia. Clarifying Cognitive Control Deficits in Psychosis via Drift Diffusion Modeling and Attractor Dynamics. Understanding the Mechanisms of Cognitive Remediation on Recovery in People With Early Psychosis: A Mediation and Moderation Analysis. The Role of Religion and Ethnic Factors in My Recovery From 10 Years of Schizophrenia and Severe Depression.
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