一名儿科患者因氨苄西林-舒巴坦引起的肝损伤。

Q2 Medicine Journal of Pediatric Pharmacology and Therapeutics Pub Date : 2023-01-01 Epub Date: 2023-12-12 DOI:10.5863/1551-6776-28.8.747

Corey Fowler, Katie Namtu

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引用次数: 0

摘要

药物诱发肝损伤（DILI）是儿科患者中罕见的药物不良反应（ADR），目前关于氨苄西林-舒巴坦诱发肝损伤的报道有限。本报告概述了一名 12 岁男性患者接受氨苄西林-舒巴坦治疗后出现的肝损伤，其特征是血清转氨酶和胆红素升高。随后停用了氨苄西林-舒巴坦，患者的肝功能检查（LFT）迅速好转。本报告描述了氨苄西林-舒巴坦诱发肝损伤的罕见不良反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Ampicillin-Sulbactam-Induced Liver Injury in a Pediatric Patient.

Drug-induced liver injury (DILI) is a rare adverse drug reaction (ADR) in pediatric patients and limited reports exist examining ampicillin-sulbactam-induced liver injury. This report summarizes a 12-year-old male who received ampicillin-sulbactam and subsequently developed liver injury characterized by elevated serum aminotransferases and bilirubin. Ampicillin-sulbactam was subsequently discontinued and the patient's liver function tests (LFTs) rapidly improved. This report describes the rare adverse reaction of ampicillin-sulbactam-induced liver injury.

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来源期刊

Journal of Pediatric Pharmacology and Therapeutics Medicine-Pediatrics, Perinatology and Child Health

CiteScore

2.40

自引率

0.00%

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期刊介绍： The Journal of Pediatric Pharmacology and Therapeutics is the official journal of the Pediatric Pharmacy Advocacy Group. JPPT is a peer-reviewed multi disciplinary journal that is devoted to promoting the safe and effective use of medications in infants and children. To this end, the journal publishes practical information for all practitioners who provide care to pediatric patients. Each issue includes review articles, original clinical investigations, case reports, editorials, and other information relevant to pediatric medication therapy. The Journal focuses all work on issues related to the practice of pediatric pharmacology and therapeutics. The scope of content includes pharmacotherapy, extemporaneous compounding, dosing, methods of medication administration, medication error prevention, and legislative issues. The Journal will contain original research, review articles, short subjects, case reports, clinical investigations, editorials, and news from such organizations as the Pediatric Pharmacy Advocacy Group, the FDA, the American Academy of Pediatrics, the American Society of Health-System Pharmacists, and so on.