胆囊原发性恶性黑色素瘤合并多处转移的病例报告。

IF 0.7 Q4 PATHOLOGY Case Reports in Pathology Pub Date : 2023-12-12 eCollection Date: 2023-01-01 DOI:10.1155/2023/4847053
Steven H Adams, Erinn Luo, Daniel Lozeau, Xiaoyun Wen
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引用次数: 0

摘要

胆囊原发性恶性黑色素瘤是一种极其罕见的肿瘤,迄今为止文献中描述的病例约有 39 例。然而,自1907年报道首例恶性黑色素瘤以来,胆囊受累是原发性还是转移性一直存在争议。在此,我们报告了一例胆囊原发性恶性黑色素瘤病例。一名 52 岁的男性因右上腹疼痛到急诊科就诊,超声波检查发现大部分胆囊内充满肿瘤性淤积物,胆囊壁可能增厚。因推测为急性胆囊炎,患者接受了腹腔镜胆囊切除术。胆囊组织病理学检查显示,恶性黑色素瘤源于胆囊粘膜。进一步的临床检查排除了其他原发部位,支持胆囊原发性恶性黑色素瘤的诊断。
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A Case Report of Primary Malignant Melanoma of the Gallbladder with Multiple Metastases.

Primary malignant melanoma of the gallbladder is an extremely rare tumor with approximately 39 cases described in the literature so far. However, since the first case was reported in 1907, it remains controversial whether gallbladder involvement in malignant melanoma is primary or metastatic. Here, we report a case of primary malignant melanoma of the gallbladder. A 52-year-old male presented to the emergency department with right upper quadrant abdominal pain and was found to have tumefactive sludge filling the majority of the gallbladder with possible gallbladder wall thickening on ultrasonography. A laparoscopic cholecystectomy was performed for presumed acute cholecystitis. Histopathologic examination of the gallbladder revealed malignant melanoma arising from the mucosa of the gallbladder. Further clinical investigation excluded other primary sites, supporting a diagnosis of primary malignant melanoma of the gallbladder.

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