滥用 1,4-丁二醇的后果:综述。

Psychopharmacology bulletin Pub Date : 2023-12-04
VYu Skryabin, YuB Shevtsova, E A Novoselova
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引用次数: 0

摘要

γ-羟丁酸(GHB)及其前体1,4-丁二醇(1,4-BD)和γ-丁内酯(GBL)都是强效的中枢抑制剂,因具有兴奋和松弛作用而被广泛非法使用。文章回顾了有关 1,4-BD 滥用、中毒临床表现、成瘾发展和谵妄的文献。现有证据表明,1,4-丁二酸是一种具有自身精神活性作用的物质,成瘾可能性很高,并可能出现严重的戒断症状。
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Consequences of 1,4-Butanediol Misuse: A Review.

Gamma-hydroxybutyrate (GHB), along with its precursors, 1,4-butanediol (1,4-BD) and gamma-butyrolactone (GBL), are potent central depressant agents widely illicitly used for their euphoric and relaxant effects. The article presents a review of the literature on the 1,4-BD misuse, the clinical picture of intoxication, development of addiction and delirium. The available evidence shows that 1,4-BD is a substance with its own psychoactive effects, a high addiction potential and potentially severe withdrawal symptoms.

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