金纳米粒子作为治疗剂载体的兴起。

IF 1.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Acta Chimica Slovenica Pub Date : 2023-11-02 DOI:10.17344/acsi.2023.8216
Satyanarayan Pattnaik, Chandrashekar Thalluri, Kalpana Swain
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引用次数: 0

摘要

纳米粒子的直径只有纳米大小,因此是最简单的结构组件。纳米粒子通常是原子或分子,它们结合在一起时产生的半径(或直径)小于 100 纳米。纳米技术的最新发展为在纳米尺度上研究和监测各种医学和生物过程提供了广泛的方法。纳米粒子可直接将药物带入癌细胞,从而帮助诊断和治疗癌症等疾病。它们还可用于检测体内的疾病生物标志物,帮助进行早期诊断。这些数据很可能会对生物学和医学产生积极影响。纳米粒子有可能被用于治疗学应用和靶向给药。这将大大改善患者的治疗效果,减少诊断和治疗疾病所需的时间、精力和金钱。它还可以减少治疗的副作用,提供更精确、更有效的治疗。生物医学应用的纳米粒子包括聚合物和金属纳米粒子、脂质体和胶束、树枝状分子和量子点等。在这些纳米粒子中,金纳米粒子已成为一种前景广阔的药物输送应用平台。金纳米粒子具有良好的生物相容性、稳定性以及可调的物理和化学特性,因此在药物递送应用中具有很大的优势。本综述深入探讨了金纳米粒子合成和给药应用的各种方法。
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Rise of gold nanoparticles as carriers of therapeutic agents.

A nanoparticle is the simplest structural component due to its nanometer-sized diameter. Nanoparticles are typically atoms or molecules that generate a radius (or diameter) of less than 100 nm when bonded collectively. The latest developments in nanotechnology provide a wide range of methods for studying and monitoring various medical and biological processes at the nanoscale. Nanoparticles can help diagnose and treat diseases, such as cancer, by carrying drugs directly to cancer cells. They can also be used to detect disease biomarkers in the body, helping to provide early diagnosis. It is likely that the data will have a positive effect on biology and medicine. It is plausible that nanoparticles could be used in theranostic applications and targeted drug delivery. This could significantly improve patient outcomes and reduce the amount of time, effort, and money needed to diagnose and treat diseases. It could also reduce the side effects of treatments, providing more precise and effective treatments. Nanoparticles for biomedical applications include polymeric and metal nanoparticles; liposomes and micelles; dendrimers and quantum dots; etc. Among the nanoparticles, gold nanoparticles have emerged as a promising platform for drug delivery applications. Gold nanoparticles are highly advantageous for drug delivery applications due to their excellent biocompatibility, stability, and tunable physical and chemical properties. The present review provides an in-depth discussion of the various approaches to gold nanoparticle synthesis and drug delivery applications.

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来源期刊
Acta Chimica Slovenica
Acta Chimica Slovenica 化学-化学综合
CiteScore
2.50
自引率
25.00%
发文量
80
审稿时长
1.0 months
期刊介绍: Is an international, peer-reviewed and Open Access journal. It provides a forum for the publication of original scientific research in all fields of chemistry and closely related areas. Reviews, feature, scientific and technical articles, and short communications are welcome.
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