踝关节骨折手术后使用止血带对术后阿片类药物消耗量的影响--一项回顾性队列研究。

IF 1.5 Q4 CLINICAL NEUROLOGY Scandinavian Journal of Pain Pub Date : 2023-11-16 eCollection Date: 2024-01-01 DOI:10.1515/sjpain-2023-0051
Pasi M Lehto, Tero Kortekangas, Merja Vakkala, Pasi Ohtonen, Emma-Sofia Nyman, Kaisu Karvonen, Janne Liisanantti, Timo I Kaakinen
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引用次数: 0

摘要

目的:在踝关节骨折手术中经常使用气动止血带,以减少出血并提高手术视野的可见度。使用止血带会引起机械性疼痛和缺血性疼痛。本研究的主要目的是评估止血带时间对踝关节骨折术后阿片类药物消耗量的影响:我们回顾性地查阅了 2014-2016 年间 586 名接受踝关节骨折手术治疗的成年患者的档案。我们对止血带时间对术后 24 小时内阿片类药物消耗量的影响进行了事后评估。根据止血带时间将患者分为四等分(4-43 分钟;44-58 分钟;59-82 分钟;≥83 分钟)。采用多变量线性回归分析评估结果:结果:486名患者使用了止血带。在术后最初 24 小时内,使用止血带与术后阿片类药物总用量增加 5.1 毫克(95 % CI 1.6-8.5;p=0.004)有关。与止血带使用时间为4-43分钟的患者相比,止血带使用时间超过83分钟与术后羟考酮平均用量增加5.4毫克(95 % CI 1.2-9.7;p=0.012)有关:结论:在踝关节骨折固定手术后24小时的术后随访中,使用止血带和延长止血带时间与较高的术后阿片类药物消耗量有关。由于该研究具有回顾性,北奥斯特罗博特尼亚卫生区机构审查委员会免除了伦理审批和知情同意的要求。
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The effect of tourniquet use on postoperative opioid consumption after ankle fracture surgery - a retrospective cohort study.

Objectives: A pneumatic tourniquet is often used during ankle fracture surgery to reduce bleeding and enhance the visibility of the surgical field. Tourniquet use causes both mechanical and ischemic pain. The main purpose of this study was to evaluate the effect of tourniquet time on postoperative opioid consumption after ankle fracture surgery.

Methods: We retrospectively reviewed the files of 586 adult patients with surgically treated ankle fractures during the years 2014-2016. We evaluated post hoc the effect of tourniquet time on postoperative opioid consumption during the first 24 h after surgery. The patients were divided into quartiles by the tourniquet time (4-43 min; 44-58 min; 59-82 min; and ≥83 min). Multivariable linear regression analysis was used to evaluate the results.

Results: Tourniquets were used in 486 patients. The use of a tourniquet was associated with an increase in the total postoperative opioid consumption by 5.1 mg (95 % CI 1.6-8.5; p=0.004) during the first 24 postoperative hours. The tourniquet time over 83 min was associated with an increase in the mean postoperative oxycodone consumption by 5.4 mg (95 % CI 1.2 to 9.7; p=0.012) compared to patients with tourniquet time of 4-43 min.

Conclusions: The use of a tourniquet and prolonged tourniquet time were associated with higher postoperative opioid consumption during the 24 h postoperative follow-up after surgical ankle fracture fixation. The need for ethical approval and informed consent was waived by the Institutional Review Board of Northern Ostrobothnia Health District because of the retrospective nature of the study.

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来源期刊
Scandinavian Journal of Pain
Scandinavian Journal of Pain CLINICAL NEUROLOGY-
CiteScore
3.30
自引率
6.20%
发文量
73
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