分化肌肉细胞中的信使核糖核酸--20 世纪 70 年代和 80 年代我在弗朗索瓦-格罗斯(François Gros)实验室的经历。

Pub Date : 2024-03-29 DOI:10.5802/crbiol.132
Margaret Buckingham
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引用次数: 0

摘要

1971 年底,我作为博士后加入弗朗索瓦-格罗斯的实验室,并一直作为研究科学家与他共事,直到 1987 年成为巴斯德研究所的独立小组负责人。20 世纪 70 年代初,他的实验室开始研究肌肉细胞分化,将其作为研究 mRNA 和基因调控的真核系统模型。在这篇文章中,我回顾了我们在肌肉生成方面的工作,并提到了他实验室的其他研究课题和相关人员。我一直与弗朗索瓦保持着密切联系,并向他致敬,他是法国科学界的重要人物,也是我的个人导师,为我提供了持续不断的支持。
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Messenger RNA in differentiating muscle cells-my experience in François Gros' lab in the 1970s and 80s.

I joined François Gros' laboratory as a postdoc at the end of 1971 and continued working with him as a research scientist until 1987, when I became an independent group leader at the Institut Pasteur. In the early 1970s, it was the beginning of research in his lab on muscle cell differentiation, as a model eukaryotic system for studying mRNAs and gene regulation. In this article, I recount our work on myogenesis and mention the other research themes in his lab and the people concerned. I remained in close contact with François and pay tribute to him as a major figure in French science and as my personal mentor who provided me with constant support.

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