细菌性肾病(BKD)的流行情况

D. Alontseva, A. E. Droshnev, E. Zavyalova
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摘要

相关性。细菌性肾病(BKD、冠状病毒肾炎、Di 病)的病原体是革兰氏阳性无芽孢无运动细菌 Renibacterium.salmoninarum,它是鲑科鱼类(Salmonidae)的一种常见疾病,会对水产养殖中的鱼类生产和产业发展造成重大损害,并减少野生种群的数量。本综述旨在分析细菌性肾病(BKD)在俄罗斯联邦境内以及其他国家的野生鲑鱼和水产养殖鱼类种群中的流行情况。文章介绍了 1933-2023 年期间细菌性肾病在全球和俄罗斯联邦境内的发病情况,展示了该疾病在野生种群和水产养殖鱼类中的传播数据,描述了可能的传播途径、本地和疑似感染媒介。作者考虑了在全球和俄罗斯联邦境内控制 BKD 发病率增长的措施。由于缺乏有效的疫苗和治疗方法,控制疾病传播最经济实惠的方法是及时诊断。文章介绍了弗罗茨瓦夫鱼类病理学实验室(FSC VIEV)工作人员开发的快速有效诊断方法:微凝集反应(PMA)和实时聚合酶链反应(实时 PCR)。与传统的细菌学方法不同,这些反应可以在 24 小时内指示和确定 BKD 的病原体。
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Epizootic situation of bacterial kidney disease (BKD)
Relevance. Bacterial kidney disease (BKD, corineal renal infection, Di disease), the causative agent of which is the gram–positive non-spore motionless bacterium Renibacterium.salmoninarum, is a common disease of salmon fish (Salmonidae), which causes significant damage to fish production in aquaculture and the development of the industry, as well as reduces the number of wild populations.The purpose of this review was to analyze the epizootic situation of bacterial renal disease (BKD) among wild salmon and fish populations in aquaculture on the territory of the Russian Federation, as well as in other countries.The article presents information on the incidence of BKD in the world and on the territory of the Russian Federation for the period 1933–2023, shows data on the spread of the disease among wild populations and farmed fish in aquaculture, describes possible transmission routes, native and suspected vectors of infection.Methods. The authors consider measures to control the growth of the incidence of BKD in the world and on the territory of the Russian Federation. Due to the lack of an effective vaccine and a method of treatment, the most affordable method of controlling the spread of the disease is timely diagnosis. The article describes the methods developed for fast and effective diagnostics by the staff of the Laboratory of Ichthyopathology of the FSC VIEV: microagglutination reaction (PMA) and polymerase chain reaction in real time (real-time PCR).Results. Unlike classical bacteriological methods, these reactions allow for the indication and identification of the causative agent of BKD within 24 hours.
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