在汉特-曼西民族自治区-尤格拉建立心肌梗塞患者生物样本采集系统

A. V. Morozkina, A. Vorobev, M. Y. Donnikov, L. V. Kovalenko, M. L. Safronova, A. K. Gapurova, K. Y. Nikolaev
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引用次数: 0

摘要

目的收集心肌梗塞患者的全血、白细胞悬液和基因组脱氧核糖核酸样本,用于医学基础研究和应用研究。苏尔古特国立大学医学研究所生物库中生物材料样本的采集、运输和处理均按照标准方法进行,并采用了建议、标准操作程序和国家生物库指导方针。截至 2023 年 9 月 1 日,生物库共收集了 744 份全血和白细胞悬液等分试样,并从 108 名心肌梗塞后的捐献者身上分离出 108 份基因组脱氧核糖核酸样本。生物样本库收集的等分样本被积极用于多项分子遗传学研究(基因分型、大规模平行测序)。苏尔古特国立大学的生物样本库为当前和未来的心脏病学研究项目提供了高质量的生物材料。
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Creation of a biosample collection from patients after myocardial infarction in the Khanty­ Mansi Autonomous Okrug — Yugra
Aim. Creation of a sample collection of whole blood, leukocyte suspension, genomic deoxyribonucleic acid from patients with myocardial infarction for fundamental and applied research in medicine.Materials and methods. The collection, transportation and processing of biomaterial samples in the biobank of the Medical Institute of Surgut State University were carried out according to standard methods using recommendations, standard operating procedures and national guidelines for biobanking.Results. As of September 1, 2023, the collection has collected 744 aliquots of whole blood and leukocyte suspension and isolated 108 samples of genomic deoxyribonucleic acid from 108 donors after myocardial infarction. Aliquots of samples from the biobank collection are actively used for a number of molecular genetic studies (genotyping, massively parallel sequencing).Conclusion. This biosample collection on the basis of Surgut State University provides current and future research projects in cardiology with high-quality biomaterial.
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来源期刊
Cardiovascular Therapy and Prevention
Cardiovascular Therapy and Prevention Medicine-Cardiology and Cardiovascular Medicine
CiteScore
1.70
自引率
0.00%
发文量
155
审稿时长
6-12 weeks
期刊介绍: The most important objectives of the journal are: the generalization of scientific and practical achievements in the field of cardiology, increasing scientific and practical skills of cardiologists. The scientific concept of publication does the publication of modern achievements in the field of epidemiology, prevention and treatment of cardiovascular diseases, the results of research, national and international clinical trials. For publication in the journal are invited both domestic and foreign scientists and clinicians working in the field of cardiology, as well as doctors of other specialties. The magazine covers various issues in cardiology and related specialties. Each issue is prepared by Executive editor of the issue, a respected specialist in the field of epidemiology, prevention and treatment of cardiovascular diseases. The main focus of the publication — scientific articles on original research, the pharmacotherapy of cardiovascular disease, new diagnostic methods. All members of the group of authors should meet all four criteria of authorship set forth in the ICMJE recommendations: 1) concept and design development or data analysis and interpretation, and 2) manuscript justification or verification of critical intellectual content, and 3) final approval for publication of the manuscript, and 4) consent to be responsible for all aspects of the work, and assume that issues relating to the thoroughness and diligent execution of any part of the study submitted are duly investigated and resolved. Great importance the editors attached to the preparation of scientific papers by groups of authors at a high level, literacy, authors, and their ownership information, availability of research results not only to colleagues in Russia, but also abroad.
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