新型胚胎选择策略--找到正确的平衡点

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Frontiers in reproductive health Pub Date : 2023-12-15 DOI:10.3389/frph.2023.1287621
A. Polyakov, G. Rozen, Chris Gyngell, Julian Savulescu
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引用次数: 0

摘要

在体外受精(IVF)过程中,使用新技术选择胚胎有可能提高怀孕和生下健康孩子的几率。然而,重要的是要意识到过早使用这些技术可能带来的潜在风险和意外后果。本文讨论了在试管婴儿中使用新型胚胎选择技术的伦理考虑因素,包括基因检测和其他技术的日益普及,并认为使用这些技术优先移植胚胎是可以接受的,但根据未经证实的先进技术丢弃胚胎则是不可接受的。我们提供了几个历史案例,说明了可能存在的危害,在这些案例中,怀孕的总体几率可能会降低,一些患者可能会完全失去生儿育女的机会。我们强调必须谨慎行事,采取平衡的方法,确保这些技术的益处大于任何潜在的危害。我们还强调了患者在生育决策中的自主权,尤其是在利用新技术获得的信息并不精确的情况下。
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Novel embryo selection strategies—finding the right balance
The use of novel technologies in the selection of embryos during in vitro fertilisation (IVF) has the potential to improve the chances of pregnancy and birth of a healthy child. However, it is important to be aware of the potential risks and unintended consequences that may arise from the premature implementation of these technologies. This article discusses the ethical considerations surrounding the use of novel embryo selection technologies in IVF, including the growing uptake of genetic testing and others, and argues that prioritising embryos for transfer using these technologies is acceptable, but discarding embryos based on unproven advances is not. Several historical examples are provided, which demonstrate possible harms, where the overall chance of pregnancy may have been reduced, and some patients may have missed out on biological parenthood altogether. We emphasise the need for caution and a balanced approach to ensure that the benefits of these technologies outweigh any potential harm. We also highlight the primacy of patients' autonomy in reproductive decision-making, especially when information gained by utilising novel technologies is imprecise.
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CiteScore
2.00
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0.00%
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审稿时长
13 weeks
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