T. H. Q. Ho, Minh That Ton, Viet Lan Nguyen, Hung Manh Pham, S. Hoang, Nhan Thanh Vo, Thai Quoc Nguyen, Linh Tran Pham, Ton Duy Mai, Thang Huy Nguyen
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引用次数: 0
摘要
在亚洲,尤其是越南,房颤是一种常见的心律失常,与中风和全身性栓塞的高风险有关。心房颤动患者为预防中风而进行的抗凝治疗可能会导致出血并发症。要有效控制心房颤动,采取适当的抗凝治疗和应对可改变的风险因素至关重要。越南临床医生对非维生素 K 拮抗剂口服抗凝药(NOACs)尤其感兴趣,这是心房颤动治疗的最新进展。然而,由于缺乏对 NOACs 进行头对头比较的试验,因此选择特定的 NOACs 具有挑战性。本综述旨在全面概述 NOACs 用于房颤卒中预防的现有临床证据,以帮助临床医生做出明智的决定并改善房颤患者的治疗效果。综述的第一部分将介绍越南心房颤动的现状,重点关注心房颤动的患病率,并强调临床实践中存在的差距。此外,这一部分还将广泛讨论心房颤动中风一级和二级预防的抗凝策略。
Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 1
In Asia, especially Vietnam, AF is a common arrhythmia and is linked to a higher risk of stroke and systemic embolism. Anticoagulation therapy for stroke prevention in AF patients can result in bleeding complications. To effectively manage AF, adopting appropriate anticoagulation and addressing modifiable risk factors are crucial. Vietnamese clinicians are particularly interested in non-vitamin K antagonist oral anticoagulants (NOACs), a recent development in AF treatment. However, the lack of head-to-head trials comparing NOACs makes selecting a specific NOAC challenging. This review aims to provide a comprehensive overview of the available clinical evidence on NOACs for stroke prevention in AF to assist clinicians in making informed decisions and improving treatment outcomes in patients with AF. The first part of this review will present the current landscape of AF in Vietnam, focusing on AF prevalence and highlighting gaps in clinical practice. Furthermore, this part extensively discusses the anticoagulation strategy for both primary and secondary stroke prevention in AF.