2015年DR SOETOMO医院感染登革热病毒儿童的营养状况、血红蛋白、白细胞、血小板、血细胞比容、白蛋白和血清学检验概况

Zakirah Zuhra
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摘要

登革热病毒感染(DVI)会引发宿主血液学、生物化学和免疫学方面的变化,影响血红蛋白(Hb)、白细胞(WBC)、血小板(Plt)、血细胞比容(Hct)、白蛋白(Alb)、IgM、IgG 和 NS1Ag 登革热等变量。本研究旨在调查登革热患者的人口统计学和临床特征,考虑的因素包括性别、年龄、营养状况、血红蛋白(Hb)、白细胞(WBC)、血小板(Plt)、血细胞比容(Hct)、白蛋白(Alb)、登革热血清学检测和登革热分期。采用横断面描述性方法,对 74 名受试者的病历进行了分析。受试者被分为 DF(33.78%)、DHF I(27.03%)、DHF II(4.05%)、DHF III(25.68%)和 DHF IV(9.46%)。受试者的年龄主要集中在 6-12 岁(48.65%),男性居多(58.11%)。大多数患者的营养状况正常(50%),女性和男性的营养状况均正常(分别为 32.26% 和 62.79%),其中以 DF 患者为主(分别为 14.86% 和 28.92%)。营养过剩发生在 DF、无休克的 DHF 和休克的 DHF 中,比例分别为 12.5%、33.33% 和 54.17%。DF 主要发生在年龄小于 6 岁的患者中(17.57%),而 DHF I、DHF II 和 DHF III 则更常见于年龄在 6-12 岁的患者中(14.86%、2.70% 和 16.22%),DHF IV 则发生在年龄小于 6 岁的患者中(8.11%)。主要研究结果显示,从 DF 到 DHF,白细胞水平均有所上升,74 名 DVI 患者中有 38 人出现白细胞减少。DVI 阶段与 Plt 水平呈反比。DHF 患者的 Hct 水平升高,Alb 水平相对较低。原发性感染在 DF 中更为常见,而继发性感染则主要发生在伴有休克的 DHF 中。该研究还注意到,2015年泗水苏托莫博士综合医院的患者在不同DVI阶段的营养过剩发生率存在差异。
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PROFILE OF NUTRITIONAL STATUS, HEMOGLOBIN, LEUKOCYTES, PLATELET, HEMATOCRIT, ALBUMIN AND SEROLOGY TEST IN CHILDREN INFECTED WITH DENGUE VIRUS AT DR SOETOMO HOSPITAL YEAR 2015
The Dengue Virus Infection (DVI) triggers changes in the host's hematological, biochemical, and immunological aspects, affecting variables like hemoglobin (Hb), leukocytes (WBC), platelets (Plt), hematocrit (Hct), albumin (Alb), IgM, IgG, and NS1Ag Dengue. This study aims to investigate the demographic and clinical characteristics of DVI patients, considering factors such as gender, age, nutritional status, Hb, WBC, Plt, Hct, Alb, dengue serologic tests, and DVI stage. Using a cross-sectional descriptive approach, medical records of 74 subjects were analyzed. Subjects were categorized as DF (33.78%), DHF I (27.03%), DHF II (4.05%), DHF III (25.68%), and DHF IV (9.46%). Predominantly, subjects were aged 6-12 years (48.65%) and predominantly male (58.11%). Most patients had a normal nutritional status (50%), seen in both females and males (32.26%, 62.79%), with DF being dominant (14.86%, 28.92%). Over-nutrition occurred in DF, DHF without shock, and DHF with shock at rates of 12.5%, 33.33%, and 54.17%. DF prevailed in patients aged <6 years (17.57%), while DHF I, DHF II, DHF III were more common in those aged 6-12 years (14.86%, 2.70%, 16.22%), and DHF IV in those aged <6 years (8.11%). Key findings revealed increased Hb levels from DF to DHF, with 38 of 74 DVI patients exhibiting leukopenia. The DVI stage showed an inverse correlation with Plt levels. Hct levels rose in DHF patients, and they had relatively low Alb levels. Primary infections were more frequent in DF, while secondary infections were predominant in DHF with shock. The study also noted variations in over-nutrition prevalence across DVI stages among patients at Dr. Soetomo General Hospital Surabaya in 2015.
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PROFILE OF NUTRITIONAL STATUS, HEMOGLOBIN, LEUKOCYTES, PLATELET, HEMATOCRIT, ALBUMIN AND SEROLOGY TEST IN CHILDREN INFECTED WITH DENGUE VIRUS AT DR SOETOMO HOSPITAL YEAR 2015 CYTOTOXICITY TEST OF BOVINE DEMINERALIZED BONE MATRIX ON HUMAN MESENCHYMAL STEM CELLS USING THE MTT ASSAY METHOD INCREASE MIGRATION OF PERIPHERAL BLOOD DERIVED ENDOTHELIAL PROGENITOR CELLS OF STABLE CORONARY ARTERY DISEASE PATIENT WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS THE EFFECT OF PLATELET-RICH PLASMA ADMINISTRATION ON PROLIFERATION AND DIFFERENTIATION OF ENDOTHELIAL PROGENITOR CELLS IN PATIENTS WITH STABLE CORONARY HEART DISEASE CHONDROREGENERATIVE POTENTIAL ON SUBCUTANEOUS IMPLANTATION OF PLATELET-RICH FIBRIN (PRF)-IMPREGNATED DECELLULARIZED BOVINE CARTILAGE SCAFFOLD
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