微量营养素与膳食和生活方式调整相结合的阿尔茨海默病治疗和部分康复新策略

IF 6.7 2区 医学 Q1 NEUROSCIENCES Progress in Neurobiology Pub Date : 2023-12-11 DOI:10.60124/j.pneuro.2023.30.02
Jin-Tao Li, Guanghui Xiu, Yueqin Zeng
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引用次数: 0

摘要

阿尔茨海默病(AD)是最常见的痴呆症病因之一,可导致记忆力减退、思维困难和行为改变。迄今为止,阿尔茨海默病一直被认为是一种老年性疾病,因此在治疗和预防方面对临床神经病学来说都是一个巨大的挑战,这不仅给患者及其家庭,也给社会带来了沉重的负担。在这篇综述中,我们提出了一种新的策略,即在临床上综合应用多种微量营养素,结合饮食和生活方式的调整,对AD患者和已经出现前驱期症状的人进行预防,甚至部分恢复AD的功能。基于这些概念,提出了证据和有益的方法。我们有希望建立一套更好、更有效的AD管理制度,以期早日降低AD的发病率,提高AD患者的生活质量。
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New Strategy of Micronutrients Combined with Dietary and Lifestyle Adjustment for Alzheimer’s Disease Therapy and Partial Restoration
Alzheimer’s disease (AD), known as one of the most common cause of dementia, could lead to memory loss, difficulty with thinking and behavioral changes. To date, AD has been continuously regarded as an incurative disease of the aged and therefore as a big challenge for clinical neurology both in the therapy and prevention, which brings about heavy burden to not only the patients and their family, but also the society. In this review, it has been proposed a new strategy that would be synthetically implemented for the prevention and even partial restoration of AD clinically, in which multiple micronutrients, combined with diet and lifestyle adjustment, were used for AD patients and people who already had the pro-phase symptoms. Based on these notions, evidence and beneficial methods are put forward. It is promising to install a better and more efficacious AD administrative system, with aim to reduce the incidence rate and elevate the life quality of AD patients in a sooner future.
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来源期刊
Progress in Neurobiology
Progress in Neurobiology 医学-神经科学
CiteScore
12.80
自引率
1.50%
发文量
107
审稿时长
33 days
期刊介绍: Progress in Neurobiology is an international journal that publishes groundbreaking original research, comprehensive review articles and opinion pieces written by leading researchers. The journal welcomes contributions from the broad field of neuroscience that apply neurophysiological, biochemical, pharmacological, molecular biological, anatomical, computational and behavioral analyses to problems of molecular, cellular, developmental, systems, and clinical neuroscience.
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