胸腔白血病常见和不常见表现的解剖学方法与放射学病理学相关性》(Anatomic Approach to Common and Uncommon Manifestations of Thoracic Leukemias with Radiologic-Pathologic Correlation)。

IF 3.8 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Radiology. Cardiothoracic imaging Pub Date : 2023-12-01 DOI:10.1148/ryct.230151
Chi Wan Koo, Livia Maria Frota Lima, Allison Kerper, Ying-Chun Lo
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引用次数: 0

摘要

白血病是以骨髓中产生异常白细胞为特征的造血恶性肿瘤。临床表现源于骨髓抑制或白血病器官浸润。淋巴腺病是胸腔内白血病最常见的直接表现。不过,白血病细胞也可能浸润肺部、胸膜、心脏、骨骼和软组织。白血病患者的肺部并发症通常包括肺炎、出血、肺水肿和白血病治疗后遗症。然而,肺部异常也可能与白血病直接相关,包括白血病肺部浸润。白血病对胸腔内部结构的直接、与治疗无关的影响将是本文成像的重点。鉴于图像解读的典型解剖方法,本文将以器官为基础,描述白血病直接导致的常见和较少见的胸腔内发现,并强调与病理学相关的成像发现。关键词白血病、肺、胸部、软组织/皮肤、血液学、骨髓 © RSNA, 2023.
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Anatomic Approach to Common and Uncommon Manifestations of Thoracic Leukemias with Radiologic-Pathologic Correlation.

Leukemias are hematopoietic malignancies characterized by the production of abnormal leukocytes in the bone marrow. Clinical manifestations arise from either bone marrow suppression or leukemic organ infiltration. Lymphadenopathy is the most common direct manifestation of intrathoracic leukemia. However, leukemic cells may also infiltrate the lungs, pleura, heart, bones, and soft tissues. Pulmonary complications in patients with leukemia typically include pneumonia, hemorrhage, pulmonary edema, and sequelae of leukemia treatment. However, pulmonary abnormalities can also be related directly to leukemia, including leukemic pulmonary infiltration. The direct, non-treatment-related effects of leukemia on intrathoracic structures will be the focus of this imaging essay. Given the typical anatomic approach for image interpretation, an organ-based depiction of common and less common intrathoracic findings directly caused by leukemic involvement is presented, emphasizing imaging findings with pathologic correlations. Keywords: Leukemia, Pulmonary, Thorax, Soft Tissues/Skin, Hematologic, Bone Marrow © RSNA, 2023.

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