84例乙胺丁醇治疗视神经病变的发生率分析。

Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) Pub Date : 1989-01-01

P De Palma, F Franco, G Bragliani, L Michetti, A Marescotti, G Pirazzoli, M Fiorenza

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引用次数: 0

摘要

作者对84例经乙胺丁醇(25mg /Kg/ Kg)治疗的肺TBC患者进行了研究。根据患者血浆锌水平分为两组:53例患者血浆锌水平大于1mg /l, 31例患者血浆锌水平小于0.7 mg/l。两组患者定期随访视力、眼底、色觉(Fransworth 100 HUE)、视野。第一组每月支付一次，第二组每两周支付一次。8例患者出现视神经病变征象。血浆锌水平较低的患者视神经病变的发生率较高。

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The incidence of optic neuropathy in 84 patients treated with ethambutol.

The authors examined 84 patients with pulmonary TBC treated with ethambutol (25 mg/Kg/die). The patients were divided into two groups on the basis of zinc plasma levels: 53 patients with zinc plasma level greater than 1 mg/l and 31 with zinc plasma levels less than 0.7 mg/l. The two groups underwent periodical follow-up of visual acuity, fundus, color vision (Fransworth 100 HUE) and visual field. The checks were monthly on the first group and fortnightly in the second. Eight patients presented signs of optic neuropathy. Patients with lower zinc plasma levels showed a higher percentage of optic neuropathy.

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Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985)

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