无智力障碍的典型半乳糖血症患者的社会认知、情绪调节和社交能力。

IF 2.6 4区 医学 Q3 NEUROSCIENCES Acta Neuropsychiatrica Pub Date : 2024-01-05 DOI:10.1017/neu.2023.61
Merel E Hermans, Gert J Geurtsen, Carla E M Hollak, Mirian C H Janssen, Janneke G Langendonk, Valerie L V Merckelbach, Esmee Oussoren, Kim J Oostrom, Annet M Bosch
{"title":"无智力障碍的典型半乳糖血症患者的社会认知、情绪调节和社交能力。","authors":"Merel E Hermans, Gert J Geurtsen, Carla E M Hollak, Mirian C H Janssen, Janneke G Langendonk, Valerie L V Merckelbach, Esmee Oussoren, Kim J Oostrom, Annet M Bosch","doi":"10.1017/neu.2023.61","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Classical galactosemia (CG) is an inborn error of galactose metabolism. Many CG patients suffer from long-term complications including poor cognitive functioning. There are indications of social dysfunction but limited evidence in the literature. Therefore, this study aims to improve our understanding of social competence in CG by investigating social cognition, neurocognition and emotion regulation.</p><p><strong>Methods: </strong>A comprehensive (neuro)psychological test battery, including self and proxy questionnaires, was administered to CG patients without intellectual disability. Social cognition was assessed by facial emotion recognition, Theory of Mind and self-reported empathy. Standardised results were compared to normative data of the general population.</p><p><strong>Results: </strong>Data from 23 patients (aged 8-52) were included in the study. On a group level, CG patients reported satisfaction with social roles and no social dysfunction despite the self-report of lower social skills. They showed deficits in all aspects of social cognition on both performance tests (emotion recognition and Theory of Mind) and self-report questionnaires (empathy). Adults had a lower social participation than the general population. Parents reported lower social functioning, less adaptive emotion regulation and communication difficulties in their children. Individual differences in scores were present.</p><p><strong>Conclusion: </strong>This study shows that CG patients without intellectual disability are satisfied with their social competence, especially social functioning. Nevertheless, deficits in social cognition are present in a large proportion of CG patients. Due to the large variability in scores and discrepancies between self- and proxy-report, an individually tailored, comprehensive neuropsychological assessment including social cognition is advised in all CG patients. Treatment plans need to be customised to the individual patient.</p>","PeriodicalId":48964,"journal":{"name":"Acta Neuropsychiatrica","volume":" ","pages":"1-12"},"PeriodicalIF":2.6000,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Social cognition, emotion regulation and social competence in classical galactosemia patients without intellectual disability.\",\"authors\":\"Merel E Hermans, Gert J Geurtsen, Carla E M Hollak, Mirian C H Janssen, Janneke G Langendonk, Valerie L V Merckelbach, Esmee Oussoren, Kim J Oostrom, Annet M Bosch\",\"doi\":\"10.1017/neu.2023.61\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Classical galactosemia (CG) is an inborn error of galactose metabolism. Many CG patients suffer from long-term complications including poor cognitive functioning. There are indications of social dysfunction but limited evidence in the literature. Therefore, this study aims to improve our understanding of social competence in CG by investigating social cognition, neurocognition and emotion regulation.</p><p><strong>Methods: </strong>A comprehensive (neuro)psychological test battery, including self and proxy questionnaires, was administered to CG patients without intellectual disability. Social cognition was assessed by facial emotion recognition, Theory of Mind and self-reported empathy. Standardised results were compared to normative data of the general population.</p><p><strong>Results: </strong>Data from 23 patients (aged 8-52) were included in the study. On a group level, CG patients reported satisfaction with social roles and no social dysfunction despite the self-report of lower social skills. They showed deficits in all aspects of social cognition on both performance tests (emotion recognition and Theory of Mind) and self-report questionnaires (empathy). Adults had a lower social participation than the general population. Parents reported lower social functioning, less adaptive emotion regulation and communication difficulties in their children. Individual differences in scores were present.</p><p><strong>Conclusion: </strong>This study shows that CG patients without intellectual disability are satisfied with their social competence, especially social functioning. Nevertheless, deficits in social cognition are present in a large proportion of CG patients. Due to the large variability in scores and discrepancies between self- and proxy-report, an individually tailored, comprehensive neuropsychological assessment including social cognition is advised in all CG patients. Treatment plans need to be customised to the individual patient.</p>\",\"PeriodicalId\":48964,\"journal\":{\"name\":\"Acta Neuropsychiatrica\",\"volume\":\" \",\"pages\":\"1-12\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-01-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Neuropsychiatrica\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1017/neu.2023.61\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Neuropsychiatrica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1017/neu.2023.61","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0

摘要

目的:典型半乳糖血症(CG)是一种先天性半乳糖代谢异常。许多半乳糖血症患者都患有长期并发症,包括认知功能低下。有迹象表明存在社交功能障碍,但文献中的证据有限。因此,本研究旨在通过调查社会认知、神经认知和情绪调节,加深我们对 CG 社交能力的了解:方法:对无智力障碍的 CG 患者进行全面的(神经)心理测试,包括自我问卷和代理问卷。社会认知通过面部情绪识别、心智理论和自我共情报告进行评估。标准化结果与普通人群的标准数据进行了比较:研究纳入了 23 名患者(8-52 岁)的数据。在群体层面上,CG 患者对社会角色表示满意,尽管自我报告的社交技能较低,但他们没有社交功能障碍。在表现测试(情绪识别和心智理论)和自我报告问卷(移情)中,他们在社会认知的各个方面都表现出缺陷。成年人的社会参与度低于普通人。家长们报告说,他们的孩子社会功能较低、情绪调节能力较差、沟通困难。得分存在个体差异:本研究表明,无智力障碍的 CG 患者对自己的社交能力,尤其是社交功能感到满意。然而,很大一部分 CG 患者在社会认知方面存在缺陷。由于评分差异较大,且自我报告与代理报告之间存在差异,因此建议对所有 CG 患者进行个体化的、全面的神经心理学评估,包括社会认知能力评估。治疗计划需要根据患者的具体情况量身定制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Social cognition, emotion regulation and social competence in classical galactosemia patients without intellectual disability.

Objective: Classical galactosemia (CG) is an inborn error of galactose metabolism. Many CG patients suffer from long-term complications including poor cognitive functioning. There are indications of social dysfunction but limited evidence in the literature. Therefore, this study aims to improve our understanding of social competence in CG by investigating social cognition, neurocognition and emotion regulation.

Methods: A comprehensive (neuro)psychological test battery, including self and proxy questionnaires, was administered to CG patients without intellectual disability. Social cognition was assessed by facial emotion recognition, Theory of Mind and self-reported empathy. Standardised results were compared to normative data of the general population.

Results: Data from 23 patients (aged 8-52) were included in the study. On a group level, CG patients reported satisfaction with social roles and no social dysfunction despite the self-report of lower social skills. They showed deficits in all aspects of social cognition on both performance tests (emotion recognition and Theory of Mind) and self-report questionnaires (empathy). Adults had a lower social participation than the general population. Parents reported lower social functioning, less adaptive emotion regulation and communication difficulties in their children. Individual differences in scores were present.

Conclusion: This study shows that CG patients without intellectual disability are satisfied with their social competence, especially social functioning. Nevertheless, deficits in social cognition are present in a large proportion of CG patients. Due to the large variability in scores and discrepancies between self- and proxy-report, an individually tailored, comprehensive neuropsychological assessment including social cognition is advised in all CG patients. Treatment plans need to be customised to the individual patient.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Acta Neuropsychiatrica
Acta Neuropsychiatrica NEUROSCIENCES-PSYCHIATRY
自引率
5.30%
发文量
30
期刊介绍: Acta Neuropsychiatrica is an international journal focussing on translational neuropsychiatry. It publishes high-quality original research papers and reviews. The Journal''s scope specifically highlights the pathway from discovery to clinical applications, healthcare and global health that can be viewed broadly as the spectrum of work that marks the pathway from discovery to global health.
期刊最新文献
The effect of azelaic acid on AlCl3-induced neurocognitive impairments and molecular changes in the hippocampus of rats. Uncovering Key Predictive Channels and Clinical Variables in the Gamma Band Auditory Steady-State Response in Early Stage Psychosis - a Longitudinal Study. The combination of a glucagon-like peptide-1 and amylin receptor agonists reduces alcohol consumption in both male and female rats. Exploring the intersection of metabolic and neuropsychiatric health. Significant haematological alterations in clozapine-treated patients: prevalence and clinical correlation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1