原发性风湿性视网膜脱离的激光辉度测量:对 2487 个病例的评估。

IF 2.3 2区 医学 Q2 OPHTHALMOLOGY Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-05-01 DOI:10.1097/IAE.0000000000004026
Caroline Gietzelt, Robert Hoerster, Petra Schiller, Saskia Hermann, Daria Kraus, Frank G Holz, Rainer Guthoff, Hansjürgen Agostini, Martin S Spitzer, Peter Wiedemann, Albrecht Lommatzsch, Karl T Boden, Ulrich Bartz-Schmidt, Sebastian Bemme, Svenja Tamm, Mathias Maier, Johann Roider, Bernd Kirchhof, Sascha Fauser, Friederike Schaub
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引用次数: 0

摘要

目的:与前瞻性、多中心、随机 PRIVENT 试验相关的探索性分析。分析流变性视网膜脱离(RRD)的激光耀斑光度与解剖学和流行病学特征之间的关系:方法:我们测量了所有 3048 名预选患者的激光耀斑值,排除了合并症患者。混合回归分析评估了年龄、性别、晶状体状态、RRD的存在和程度等因素对激光耀斑的影响强度:结果:男性(65.8%)的 RRD 发生率高于女性(34.2%,p):结果表明,影响激光耀斑的因素可能比之前假设的要多。这可能会限制耀斑对 PVR 和视网膜再脱落的预测价值。
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LASER FLARE PHOTOMETRY IN PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT: An Evaluation of 2,487 Cases.

Purpose: Exploratory analysis associated with the prospective, multicenter, randomized PRIVENT trial. To characterize the associations between laser flare photometry and anatomical and epidemiological features of rhegmatogenous retinal detachment (RRD).

Methods: The authors measured laser flare values of all 3,048 prescreened patients excluding those with comorbidities. A mixed regression analysis evaluated the strength of the influencing factors like age, sex, lens status, and presence and extent of RRD on laser flare.

Results: Rhegmatogenous retinal detachment was more frequent in men (65.8%) than in women (34.2%, P < 0.001) and in right (52%) than in left eyes (48%, P = 0.045). Phakic RRD affected less quadrants and was less likely to be associated with macula-off status than pseudophakic RRD (48.4% vs. 58.0% macula off, 23% vs. 31% ≥3 quadrants, P < 0.001). Laser flare of affected eyes was significantly higher compared with fellow eyes (12.6 ± 15.2 vs. 8.3 ± 7.4 pc/ms, P < 0.001). The factors age, sex, lens status, presence of RRD, and the number of quadrants affected were independent influencing factors on laser flare. R 2 was 0.145 for phakic and 0.094 for pseudophakic eyes.

Conclusion: The results indicate that there may be more factors affecting laser flare than previously assumed. This might limit flare as predictive value for PVR and retinal redetachment.

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来源期刊
CiteScore
5.70
自引率
9.10%
发文量
554
审稿时长
3-6 weeks
期刊介绍: ​RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.
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