{"title":"在凝乳废水中合成香豆素-3-羧酸:一种绿色方法","authors":"N. B. Sonawane, J. Rajput, Dilip Ramsing Patil","doi":"10.5155/eurjchem.14.4.439-444.2471","DOIUrl":null,"url":null,"abstract":"An efficient and green protocol has been developed for the synthesis of derivatives of coumarin-3-carboxylic acid using waste curd water as a catalytic solvent. Curd water successfully catalyzes the reaction of 2-hydroxybenzaldehydes with dimethyl malonate under ultrasonic irradiation (40 °C) to construct different scaffolds of coumarin-3-carboxylic acid, with good to outstanding yields. The use of biodegradable solvents, sustainability, low reaction duration, mild reaction conditions without metals and Lewis acids, excellent yields, and compatibility with a wide range of electronically diverse substrates are all advantages of this synthesis process. Acidic curd water, which acts as a biological catalyst as well as a solvent for the reaction under ultrasonic irradiation, may be a better green alternative to some standard methods for synthesizing coumarin-3-carboxylic acids.","PeriodicalId":11778,"journal":{"name":"European Journal of Chemistry","volume":"120 27","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis of coumarin-3-carboxylic acids in waste curd water: A green approach\",\"authors\":\"N. B. Sonawane, J. Rajput, Dilip Ramsing Patil\",\"doi\":\"10.5155/eurjchem.14.4.439-444.2471\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"An efficient and green protocol has been developed for the synthesis of derivatives of coumarin-3-carboxylic acid using waste curd water as a catalytic solvent. Curd water successfully catalyzes the reaction of 2-hydroxybenzaldehydes with dimethyl malonate under ultrasonic irradiation (40 °C) to construct different scaffolds of coumarin-3-carboxylic acid, with good to outstanding yields. The use of biodegradable solvents, sustainability, low reaction duration, mild reaction conditions without metals and Lewis acids, excellent yields, and compatibility with a wide range of electronically diverse substrates are all advantages of this synthesis process. Acidic curd water, which acts as a biological catalyst as well as a solvent for the reaction under ultrasonic irradiation, may be a better green alternative to some standard methods for synthesizing coumarin-3-carboxylic acids.\",\"PeriodicalId\":11778,\"journal\":{\"name\":\"European Journal of Chemistry\",\"volume\":\"120 27\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5155/eurjchem.14.4.439-444.2471\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5155/eurjchem.14.4.439-444.2471","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Synthesis of coumarin-3-carboxylic acids in waste curd water: A green approach
An efficient and green protocol has been developed for the synthesis of derivatives of coumarin-3-carboxylic acid using waste curd water as a catalytic solvent. Curd water successfully catalyzes the reaction of 2-hydroxybenzaldehydes with dimethyl malonate under ultrasonic irradiation (40 °C) to construct different scaffolds of coumarin-3-carboxylic acid, with good to outstanding yields. The use of biodegradable solvents, sustainability, low reaction duration, mild reaction conditions without metals and Lewis acids, excellent yields, and compatibility with a wide range of electronically diverse substrates are all advantages of this synthesis process. Acidic curd water, which acts as a biological catalyst as well as a solvent for the reaction under ultrasonic irradiation, may be a better green alternative to some standard methods for synthesizing coumarin-3-carboxylic acids.