乳腺癌患者化疗引起的周围神经病变的锻炼计划:病例研究

Khulood Alrashid, Shahd AlShehri
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引用次数: 0

摘要

背景:乳腺癌是全球妇女最常见的癌症之一,2015 年约有 57 万人死于乳腺癌。全世界每年有超过 150 万名妇女(占癌症妇女总数的 25%)被诊断出患有乳腺癌。乳腺癌手术后最常见的并发症之一是上半身功能受限。多达 67% 的乳腺癌患者在术后会出现手臂或肩部功能障碍,包括疼痛、麻木、力量丧失和活动度降低。作为化疗的副作用,乳腺癌患者会出现化疗诱发的周围神经病变(CIPN),影响患者的平衡、生活质量和整体参与度。研究设计:本病例研究旨在强调物理治疗干预在乳腺癌患者术后化疗引起的周围神经病变治疗中的作用。病例描述沙特籍女性,55 岁,已知患有糖尿病(使用胰岛素)、高血压和深静脉血栓病史,27 年前曾服用抗凝剂。她来到联合诊所的乳腺门诊,做了所有的检查和化验,结果显示为浸润性导管癌。因左肩活动范围受限、活动能力受损和症状控制不佳,她被乳腺和内分泌门诊转至理疗科。物理治疗管理和结果:患者接受了两个阶段的康复治疗,第一阶段每周一次,持续4周;第二阶段每周三次,持续6周。运动项目包括患者教育、针对 UE 和 LE 的中低强度抗阻力治疗性运动。有氧运动;针对 UE 和 LE 的有氧自行车渐进训练以及平衡运动。第一阶段结束时,患者的关节活动度和疼痛明显改善;第二阶段康复计划结束时,患者的平衡能力(使用 BBS)、功能能力和 QOL(使用 FACT-B)均有所改善。讨论本病例研究表明,包括治疗性运动、中低强度阻力运动、有氧运动、平衡运动在内的物理治疗运动项目对乳腺癌患者来说是一项有效的项目,因为它能改善患者的CIPN,最大限度地减少患者的依赖性,提高患者的生活质量。
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Exercises Program in Breast Cancer Patient with Chemotherapy Induced Peripheral Neuropathy: A Case Study
Background: Breast cancer is one of the most common cancers in women worldwide, accounting for approximately 570,000 deaths in 2015. Over 1.5 million women (25% of all women with cancer) are diagnosed with breast cancer every year throughout the world. One of the most common complications after breast cancer surgery is functional limitation of the upper body. Up to 67% of breast cancer patients experience arm or shoulder impairment, including pain, numbness, loss of strength, and reduced ROM, after surgery. Breast cancer patients are presenting with chemo-induced peripheral neuropathy (CIPN) that is impacting their balance, quality of life, and overall participation, as a side effect of chemotherapy treatment. Study Design: This case study was used to highlight the role of physical therapy interventions in the management of Breast cancer patient after surgery with chemo-induced peripheral neuropathy. Case Description: A 55-years-old Saudi female, known case of diabetes mellitus on insulin, hypertension and history of DVT 27 years back on anticoagulant. She came to the combined clinic breast clinic and all workup and investigations were done and showed invasive ductal carcinoma. Referred to physical therapy department by breast and endocrine clinic for left shoulder limited range of motion, impaired mobility and managing the symptoms. PT Management and Outcome: The patient received 2 phases of rehabilitations, phase 1 the patient was seen once a week for 4 weeks, phase 2 the patient was seen 3 times per week for 6 weeks. Exercise program of patient education, therapeutic exercise of low- to - moderate intensity resistance exercise for UE and LE. Aerobic Exercise; Cardio bike progressive training for UE and LE and balance exercise. By the end of phase 1 patient’s ROM and pain improved significantly, and by the end of phase 2 of the rehabilitation program, patient’s balance (using BBS), functional ability and QOL using (FACT-B) improved. Discussion: This case study showed that physical therapy exercise program including therapeutic exercises, low- to moderate- intensity resistance exercise, aerobic exercise, balance exercise is an effective program for breast cancer patients as it improves CIPN, minimize dependency and improved QOL.
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