原发性前列腺粘膜相关淋巴组织 (MALT) 淋巴瘤:核磁共振成像和 FDG-PET 成像发现

Yukihiro Hama
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摘要

背景:原发性前列腺粘膜相关淋巴组织(MALT)淋巴瘤是一种罕见病,目前还没有关于磁共振成像(MRI)及其与氟-18 氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)关系的报告。目的:本文旨在介绍原发性前列腺MALT淋巴瘤的MRI和FDG-PET成像结果,并讨论成像结果在诊断和治疗中的重要性。病例摘要:一名 73 岁的男性患者因出现下尿路症状和血清前列腺特异性抗原水平升高而接受了前列腺活检。组织病理学和免疫组化结果与 MALT 淋巴瘤一致。由于肿瘤局限于前列腺和邻近组织,且 PET-CT 未发现淋巴结转移,因此诊断为原发性前列腺 MALT 淋巴瘤。过渡区肿瘤沿内钝肌浸润至耻骨,核磁共振成像显示提肛肌几乎完好无损。结论在诊断原发性前列腺MALT淋巴瘤时,没有淋巴结转移或肌肉大面积破坏,但对周围组织有高度浸润是一个重要的影像学发现。关键词:鉴别诊断鉴别诊断 MRI 前列腺肿瘤
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Primary Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma of the Prostate: MRI and FDG-PET Imaging Findings
Background: Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the prostate is a rare condition, and there is no report on magnetic resonance imaging (MRI) and its relationship with fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET). Objectives: The purpose of this article is to present the MRI and FDG-PET imaging findings of primary MALT lymphoma of the prostate and discuss the imaging findings’ importance in the diagnosis and management. Case summaries: A 73-year-old male patient underwent a prostate biopsy for lower urinary tract symptoms and an elevated serum prostate-specific antigen level. Histopathologic and immunohistochemical findings were consistent with MALT lymphoma. As the tumor was confined to the prostate and adjacent tissues and no lymph node metastases were detected on PET-CT, the diagnosis was primary MALT lymphoma of the prostate. The tumor of the transitional zone infiltrated along the obturator internus muscle and into the pubic bone, the levator ani muscle was almost intact on MRI. Conclusion: The absence of lymph node metastasis or gross muscle destruction but a high degree of invasiveness into surrounding tissues is an important imaging finding in the diagnosis of primary MALT lymphoma of the prostate. Keywords: Differential Diagnosis; MRI; Prostate Neoplasms
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