Wahdini Hanifah, Yosie Andriani, Nor Atikah Mohamed Zin, D. Ryandini, Fadzillah Adibah Abdul Majid, eginer Subhan, Tengku Sifzizul Tengku Muhammad
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引用次数: 0
摘要
肺炎是由细菌等微生物引起的呼吸道感染。目前使用抗生素治疗会导致细菌产生抗药性。另一种治疗方法是利用沿海植物。在这项研究中,对 11 种沿海植物的五个部分进行了植物化学成分筛选,并研究了它们对五种肺炎细菌的抗菌活性。冷提取先后使用正己烷和甲醇进行。分别使用几种试剂和琼脂井扩散法进行了植物化学物质定性筛选和抗菌测试。结果表明,除了蔓荆子叶外,几乎所有沿海植物的正己烷和甲醇馏分都具有抗菌活性。红景天叶的正己烷馏分活性最高。在甲醇馏分中,Syzigium grande 小枝的抗菌性能最高。植物化学筛选显示,所有活性馏分中都含有黄酮类化合物,这可能与它们的抗菌活性有关。总之,一些选定的沿海植物具有作为抗肺炎细菌制剂的潜力。
Selected Coastal Plants as Potential Treatment for Pneumonia Disease: Determination of Their Phytochemicals and Antibacterial Activity Against some Pneumonia Bacteria
Pneumonia is a respiratory infection caused by microorganisms including bacteria. Current treatment with antibiotics leads to bacterial resistance. An alternative treatment involves utilizing coastal plants. In this study, five parts of eleven coastal plants underwent phytochemicals screening and investigated for their antibacterial activity against five pneumonia bacteria. Cold extraction was performed using hexane and methanol, successively. Qualitative phytochemicals screening and antibacterial testing were done using several reagents and agar well diffusion method, respectively. The results revealed that almost all hexane and methanolic fractions from coastal plants showed antibacterial activity, except Vitex rotundifolia leaves. The highest activity was shown by hexane fraction of Rhodomyrtus tomentosa leaves. Among the methanolic fractions, Syzigium grande twigs exhibited the highest antibacterial property. Phytochemical screening revealed the presence of flavonoids in all active fractions, potentially correlating with their antibacterial activity. In summary, some selected coastal plants have the potential to act as anti-pneumonia bacteria agents.
期刊介绍:
Oriental Journal of Chemistry was started in 1985 with the aim to promote chemistry research. The journal consists of articles which are rigorously peer-reviewed. The journal was indexed in Emerging Science citation index in 2016. The Editorial board member consists of eminent international scientist in all fields of Chemistry. Details of each member and their contact information is mentioned in website. The journal has thorough ethics policies and uses plagiarism detection software(ithenticate) to screen each submission. The journal has recently partnered with publons as a part of making our reviews more transparent. The journal has recently incorporated PlumX for article level matrix. The journal is promoting research on all social and academic platforms mentioned in PlumX guidelines. The journal uses google maps to improve on the geographical distribution of Editorial board members as well as authors.