ELMO CPAP:用于治疗 COVID-19 相关急性呼吸窘迫综合征的创新型通气支持技术

IF 2.9 4区 医学 Q2 RESPIRATORY SYSTEM Jornal Brasileiro De Pneumologia Pub Date : 2023-12-26 DOI:10.36416/1806-3756/e20230227
Andréa Mazza Beliero1,2, Ana Paula Pires Lázaro3,4, Marza de Sousa Zaranza1,5, Giovanna Mazza Cruz Lima4, Álvaro Rolim Guimarães5, Nilcyeli Linhares Aragão5, Gdayllon Cavalcante Meneses5, Marcelo Alcantara Holanda5,6, Polianna Lemos Moura Moreira Albuquerque4,7, Geraldo Bezerra da Silva Júnior3,4, Paula Frassinetti Castelo Branco Camurça Fernandes2
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引用次数: 0

摘要

目的评估使用 ELMO(一种在巴西发明的无创通气头盔)是否会对严重 COVID-19 引起的低氧呼吸衰竭患者的预后产生积极影响。研究方法这是一项针对 50 名 COVID-19 重症患者的回顾性研究。研究人员收集了重症监护室入院时以及使用 ELMO 之前、期间和之后的流行病学、临床和实验室数据。根据结果将患者分为两组(成功组和失败组)。结果使用 ELMO 改善了氧合参数,如 Pao2、Fio2 和 Pao2/Fio2 比值,动脉血气分析结果显示,这有助于逐渐降低 Fio2,而不会增加 CO2。与失败组相比,成功组患者的存活时间明显更长(P < 0.001),插管需求更少(P < 0.001),住院天数更少,急性肾损伤发生率更低。结论氧合参数的明显改善、存活时间的延长(体现为插管需求的减少和死亡率的降低)以及急性肾损伤的缺失表明,ELMO CPAP 系统是治疗 ARDS 和类似临床病症的理想工具。
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ELMO CPAP: an innovative type of ventilatory support for COVID-19-related acute respiratory distress syndrome
Objective: To assess whether the use of ELMO, a helmet for noninvasive ventilation created in Brazil, had a positive impact on the prognosis of patients with hypoxemic respiratory failure caused by severe COVID-19. Methods: This is a retrospective study of 50 critically ill COVID-19 patients. Epidemiological, clinical, and laboratory data were collected on ICU admission, as well as before, during, and after ELMO use. Patients were divided into two groups (success and failure) according to the outcome. Results: ELMO use improved oxygenation parameters such as Pao2, Fio2, and the Pao2/Fio2 ratio, and this contributed to a gradual reduction in Fio2, without an increase in CO2, as determined by arterial blood gas analysis. Patients in the success group had significantly longer survival (p < 0.001), as determined by the Kaplan-Meier analysis, less need for intubation (p < 0.001), fewer days of hospitalization, and a lower incidence of acute kidney injury in comparison with those in the failure group. Conclusions: The significant improvement in oxygenation parameters, the longer survival, as reflected by the reduced need for intubation and by the mortality rate, and the absence of acute kidney injury suggest that the ELMO CPAP system is a promising tool for treating ARDS and similar clinical conditions.
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来源期刊
Jornal Brasileiro De Pneumologia
Jornal Brasileiro De Pneumologia RESPIRATORY SYSTEM-
CiteScore
3.50
自引率
14.80%
发文量
118
审稿时长
20 weeks
期刊介绍: The Brazilian Journal of Pulmonology publishes scientific articles that contribute to the improvement of knowledge in the field of the lung diseases and related areas.
期刊最新文献
Acute exacerbation of interstitial lung disease after transthoracic biopsy. Chronic lung disease of prematurity and bronchopulmonary dysplasia. Clarifying the face of cannabis lung. Correspondence about the article: Asthma in the Brazilian Unified Health Care System: an epidemiological analysis from 2008 to 2021Authors' replyAsthma in the Brazilian Unified Health Care System an epidemiological analysis from 2008 to 2021Higher Asthma Mortality in Elders and Female Subjects in Brazil A 10-year Series [abstract]. Am J Respir Crit Care. Drug-induced lung disease: a narrative review.
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