使用阻抗法检测循环障碍,确定肢体缺血程度

Valerіi Kryvonosov, Oleg Avrunin, Serhii Sander, Volodymyr Pavlov, Liliia Martyniuk, B. Zhumazhanov
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引用次数: 0

摘要

新的工程技术可以制造出诊断设备,用于预测肢体急性组织缺血的发展情况,并确定拆除止血带前的剩余时间,而解决这些任务在军事行动中尤为重要。急性肢体缺血是指血流灌注突然严重减少,威胁到肢体的存活。这种情况的发病率为每年每 10 000 人中有 1.5 例。急性缺血发生的原因是主要动脉血流受阻(栓塞、血栓形成、创伤),导致肢体新陈代谢活跃的组织(包括皮肤、肌肉和神经末梢)无法获得充足的血液供应。为了解决这些问题,文章分析了生物组织阻抗的变化。引入并使用相对电导系数(用 k 表示)作为诊断标准参数是有道理的。对相对电导率系数 k 的变化进行了实验研究,证实该系数从指数关系到线性关系的转变确定了生物细胞(组织)的存活程度和再灌注综合征发生的时刻。已经确定,如果 k 值偏离其单位值 10-15%,就可以诊断出血液灌注受损的初始过程和缺血性组织疾病的发展。k 的变化率是预测疾病进展的标准,也是治疗过程中的校正因素。
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A USAGE OF THE IMPEDANCE METHOD FOR DETECTING CIRCULATORY DISORDERS TO DETERMINE THE DEGREE OF LIMB ISCHEMIA
New engineering technologies allow the creation of diagnostic devices for predicting the development of acute tissue ischemia of the extremities and determining the residual time until the removal of the tourniquet, and solving these tasks is particularly relevant during military actions. Acute limb ischemia is a sudden critical decrease in perfusion that threatens the viability of the limb. The incidence of this condition is 1.5 cases per 10 000 people per year. Acute ischemia occurs due to the blockage of blood flow in major arteries (embolism, thrombosis, trauma), leading to the cessation of adequate blood supply to metabolically active tissues of the limb, including the skin, muscles, and nerve endings. To address these issues, the article analyzes the changes in the impedance of biological tissue. The introduction and use of the coefficient of relative electrical conductivity, denoted as k, as a diagnostic criterion parameter, are justified. Experimental studies of changes in the coefficient of relative electrical conductivity k were conducted, confirming that the transition from exponential to linear dependencies of the coefficient establishes the degree of viability of the biological cell (tissue) and the moment of occurrence of reperfusion syndrome. It has been established that a deviation of the value of k by 10–15% from its unit value diagnoses the initial process of blood perfusion impairment and the development of ischemic tissue disease. The rate of change of k serves as a criterion for predicting the progression of the disease and as a corrective factor for therapeutic treatment.
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