抑郁症和心血管疾病

Dana Končelíková Kamarádová
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摘要

6 抗精神病药物除了能有效治疗厌食症和精神分裂症状外,还能增强强迫症患者对 SSRIs 的治疗反应。7 这位患者在接受帕罗西汀和一种抗精神病药物的联合治疗后,强迫症、神经性厌食症和精神分裂型人格障碍得到了迅速缓解。然而,在停止治疗后,患者的行为逐渐恶化,显然有必要进行长期治疗。帕罗西汀与一种抗精神病药物同时使用,再次取得了快速疗效。患者接受这种治疗方案已超过 9 个月,神经性厌食症没有复发,只有轻微的心理和强迫症状,也没有出现意外的不良反应。本病例研究支持对强迫症、厌食症和精神分裂症混合诊断患者联合使用帕罗西汀和抗精神病药物进行进一步研究。
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Depression and cardiovascular disorders
cacy in the treatment of OCD.6 In addition to being effective in treating anorexia and schizotypal symptoms, antipsychotics can augment the treatment response to SSRIs in OCD.7 A rapid alleviation of this patient's OCD, anorexia nervosa and schizotypal personality disorder occurred after she was treated with a combination of paroxetine and an antipsychotic agent. When treatment was discontinued, however, the patient's behaviour gradually worsened and it became apparent that long-term treatment was necessary. Paroxetine, prescribed with an antipsychotic agent, again achieved rapid results. The patient has been receiving this treatment regimen for more 9 months, with no return of anorexia nervosa, only minor psychological and compulsive symptoms and no unexpected adverse effects. This case study supports further investigation into the use of a combination of paroxetine and an antipsychotic in patients with mixed diagnoses of OCD, anorexia and schizotypal conditions.
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