对糖尿病大鼠使用牛奶和植物替代品(如杏仁奶和燕麦奶)的比较研究

R. Ashkanani
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Results: Results revealed that almond milk were more effective in increasing the dry matter, protein, ash, fiber, carbohydrate, energy, acidity, viscosity, phenolic content and antioxidant activity. Almond milk had the highest scores for sensory properties compared to other milk treatments. The Almond milk was evaluated as hypoglycaemic agent streptozotocin-induced diabetic rats. The treatment of diabetic rats with almond milk showed a significant decreases(p<0.001) in levels of blood glucose, malondialdehyde (MDA), low density lipoprotein (LDL), cholesterol (CL), triglyceride (TG), AST, ALT , ALP, creatinin and urea and increased (p<0.001) high density lipoprotein (HDL) and total protein and albumin in comparison to diabetic rats. Unique   Contribution   to   Theory,   Practice   and Policy: This study indicates that the theory used in the study has been validated. 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摘要

目的:本研究旨在评估鸦乳、杏仁乳和燕麦乳的理化、流变、微生物、抗氧化和感官特性。 鸦乳作为对照(动物来源),其他处理由杏仁乳和燕麦乳(植物来源)制成。 研究方法将 35 只体重为 180-220 克的 Sprague Dawely 品系成年雄性白化大鼠分为以下 5 组:组(1)未经治疗的非糖尿病大鼠(阴性对照组)。组(2)糖尿病大鼠(接受链脲佐菌素(STZ),60 毫克/千克体重)(阳性对照)。组(4)糖尿病大鼠基础饮食中添加杏仁奶(10 克/天),用胃管饲喂。第(5)组糖尿病大鼠在基础饮食中添加燕麦奶(10 克/天),并通过胃管进行上皮细胞移植。 结果结果显示,杏仁奶在增加干物质、蛋白质、灰分、纤维、碳水化合物、能量、酸度、粘度、酚含量和抗氧化活性方面更有效。与其他牛奶处理相比,杏仁奶的感官特性得分最高。对杏仁露作为链脲佐菌素诱导的糖尿病大鼠的降血糖剂进行了评估。与糖尿病大鼠相比,用杏仁牛奶治疗糖尿病大鼠后,其血糖、丙二醛(MDA)、低密度脂蛋白(LDL)、胆固醇(CL)、甘油三酯(TG)、谷草转氨酶(AST)、谷丙转氨酶(ALT)、谷草转氨酶(ALP)、肌酐和尿素水平明显下降(p<0.001),而高密度脂蛋白(HDL)、总蛋白和白蛋白水平上升(p<0.001)。 对理论、实践和政策的独特贡献:这项研究表明,研究中使用的理论已得到验证。与阳性对照组(未经治疗的糖尿病大鼠)相比,糖尿病大鼠组饮用杏仁奶后,所有这些因素都得到了明显改善,这表明杏仁奶和燕麦奶对这类患者可起到预防作用。该研究可作为一项指标,用于今后就食用杏仁奶和燕麦奶等植物性牛奶替代品的重要性开展研究。政策制定者应认识到均衡饮食对健康的重要性,并在公共卫生建议中体现这一点。
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A Comparative Study of the Use of Cow's Milk and Plant-Based Alternatives Such as Almond Milk and Oat Milk on Diabetic Rats
Purpose: The present study was conducted to evaluate physicochemical, rheological, microbiological, antioxidant and sensory properties of caw, almond and oat milk.  Caw milk served as a control (animal source), and the other treatments were made from almond milk and oat milk (plant source). Methodology: Thirty five male adult albino rats of Sprague Dawely strain weighing 180- 220 g were divided into 5 groups as follows: Group (1) non-treated non- diabetic rats (negative control). Group (2) diabetic rats (received Streptozotocin (STZ), 60 mg/Kg BW) (positive control).Group (3) diabetic rats fed on basal diet with caw milk (10g/day) by epi gastric tube. Group (4) diabetic rats fed on basal diet with almond milk (10g/day) by epi gastric tube. Group (5) diabetic rats fed on basal diet with oat milk (10g/day) by epi gastric tube. Results: Results revealed that almond milk were more effective in increasing the dry matter, protein, ash, fiber, carbohydrate, energy, acidity, viscosity, phenolic content and antioxidant activity. Almond milk had the highest scores for sensory properties compared to other milk treatments. The Almond milk was evaluated as hypoglycaemic agent streptozotocin-induced diabetic rats. The treatment of diabetic rats with almond milk showed a significant decreases(p<0.001) in levels of blood glucose, malondialdehyde (MDA), low density lipoprotein (LDL), cholesterol (CL), triglyceride (TG), AST, ALT , ALP, creatinin and urea and increased (p<0.001) high density lipoprotein (HDL) and total protein and albumin in comparison to diabetic rats. Unique   Contribution   to   Theory,   Practice   and Policy: This study indicates that the theory used in the study has been validated. Consumption of almond milk in diabetic rat groups caused significant improvement in all these factors, compared to the positive control group (untreated diabetic rats), indicating that almond and oat milk can play a preventive role in such patients. It can be used as an indicator to establish future studies on the importance of consuming plant-based alternatives to milk, such as almond milk and oat milk. Policy makers should recognize the importance of a balanced diet for health in which plant-based alternatives are available and reflect this in public health recommendations.
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