代谢综合征患者颈动脉内膜厚度与成纤维细胞生长因子结合蛋白-3 之间的关系

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Istanbul Medical Journal Pub Date : 2023-11-30 DOI:10.4274/imj.galenos.2023.19626
Goncagul Akdag, Esma Güldal Altunoğlu
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引用次数: 0

摘要

组(P=0.049)。结论在我们的研究中,血清 FGFBP-3 水平与 CIMT 之间没有关系。但是,FGFBP-3 与高 SBP 和糖尿病之间存在关系。我们认为,FGFBP-3 能稳定内源性 FGF21 的生物活性,因此可能对代谢性疾病(如非酒精性脂肪肝和 2 型糖尿病)有显著的治疗效果。
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Relationship between Carotid Intima-Media Thickness and Fibroblast Growth Factor Binding Protein-3 in Patients with Metabolic Syndrome
group (p=0.049). Conclusion: In our study, there was no relationship between serum FGFBP-3 levels and CIMT. However, there was a relationship between FGFBP-3 and high SBP and diabetes. We believe that FGFBP-3 can stabilize the bioactivity of endogenous FGF21 and therefore may have significant therapeutic benefits in metabolic diseases such as non-alcoholic fatty liver disease and type 2 DM.
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来源期刊
Istanbul Medical Journal
Istanbul Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
0.30
自引率
0.00%
发文量
46
审稿时长
18 weeks
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