脑单发纤维瘤:病例报告

Valeria Antuanne Ortiz Ramos, Nora Nicole Itusaca Dueñas, Lucia Victoria Ulloa Ordoñez, Ricardo Romulo Paredes Pacual, Jonathan Joel Torres Canqui, Leslie Estefany Yovera Orellana, J. V. Vela Ruiz
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引用次数: 0

摘要

导言:孤立性纤维瘤(SFTs)是一种罕见的间叶肿瘤,虽然通常发生在内脏胸膜,但偶尔也会出现在颅腔内。此外,它们还具有高转移率和高复发率的特点。病例报告:本病例为一名 59 岁男性患者,头痛和肾上腺皮质发育迟缓病史长达 3 个月。计算机断层扫描显示,新形成肿瘤浸润鼻腔、乙状窦和前颅窝,累及左额叶。患者接受了两次探查性颅骨切除术,术中诊断为高级别胶质瘤和 SFT。为了精确诊断,对其进行了免疫组化检查,结果与单发纤维瘤一致。本文对该病例进行了分析,尤其侧重于组织病理学方面、该肿瘤的不寻常位置及其多变的临床表现。
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SOLITARY FIBROUS TUMOR OF THE BRAIN: A CASE REPORT
Introduction: Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that, although typically develop in the visceral pleura, occasionally occur in the intracranial cavity. Furthermore, they are characterized by high rates of metastasis and recurrence. Case Report: We present the case of a 59-year-old male patient with a 3-month history of headache and bradyphrenia. Computed tomography revealed a neoformative tumor infiltrating the nasal cavity, ethmoid sinuses, and anterior cranial fossa, involving the left frontal lobe. The patient underwent two exploratory craniectomies, during which diagnoses suggestive of high-grade glial neoplasia and SFT were made. For precise diagnosis, immunohistochemistry was performed, which was consistent with solitary fibrous tumor. The case is analyzed, focusing particularly on histopathological aspects, the unusual location of this tumor, and its variable clinical manifestations.
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