有无糖尿病的缺血性心脏病患者颈动脉的特征

Akm Mustafizur Rahman, Farzana Sharmin, Md Mainul Islam, Mohammed Mohiuddin Shoman, Kaspia Khan
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引用次数: 0

摘要

背景:患有或未患有糖尿病的缺血性心脏病患者的冠状动脉受累情况各不相同。研究目的本研究旨在评估糖尿病或非糖尿病缺血性心脏病患者颈动脉的特征。研究方法:本病例对照研究在孟加拉国达卡班加班杜-谢赫-穆吉布医科大学心脏病学系进行。研究时间为 2003 年 7 月至 2005 年 6 月,为期两年。本研究选择了接受冠状动脉造影术的冠状动脉疾病或缺血性心脏病和糖尿病患者作为病例。在对照组中,年龄、性别与接受 CAG 检查的非糖尿病 IHD 患者相匹配。每位患者在进入研究时都接受了详细的病史和体格检查。对心电图、胸部 X 光片、超声心动图、血糖(空腹)、75 毫克葡萄糖或早餐后 2 小时的血液进行分析。所有患者均采用改良 Seldinger 技术从股动脉入路进行冠状动脉造影。通过猎人头或右侧朱德金导管,在标准的正视、侧视和斜视下进行选择性和非选择性颈动脉造影。结果:本研究共纳入 100 名患者。其中 50 名患者为冠状动脉疾病合并糖尿病,另外 50 名患者为冠状动脉疾病合并糖尿病。研究还对病变的形态特征进行了评估。结果发现,糖尿病组患者的平均年龄为 57.48 岁,标准差为 6.04;非糖尿病组患者的平均年龄为 55.64 岁,标准差为 6.34;整个研究人群的平均年龄为 56.56 岁,标准差为 6.49。非配对 t 检验值为 0.158,差异不显著(P>0.05)。常见的病变部位为颈动脉分叉、颈内动脉、颈总动脉和颈外动脉,分别为 13 例、9 例、4 例和 1 例。DM组受累血管右侧9例(18.0%),左侧6例(12.0%),两侧均受累的有3例(6.0%);NDM组受累血管右侧5例(10.0%),左侧3例(6.0%),两侧均受累的有1例(2.0%)。据观察,在 100 名研究对象中,DM 组有 10 例颈动脉复杂病变,NDM 组有 4 例。脑震荡:总之,病变的常见部位是颈动脉分叉和颈内动脉,主要在右侧。最新医学研究杂志》,2023 年 1 月;10(1):7-12
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Characteristics of Carotid Artery among Ischemic Heart Disease Patients with or without Diabetes Mellitus
Background: Involvement of coronary artery can vary among the ischemic heart disease patients with or without diabetes mellitus. Objective: The purpose of the present study was to assess the characteristics of carotid artery among ischemic heart disease patients with or without diabetes mellitus. Methodology: This case-control study was conducted in the Department of Cardiology at Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. The study was carried out from July 2003 to June 2005 for a period of two years. Patients who had coronary artery diseases or ischemic heart diseases and diabetes mellitus undergoing coronary angiography were selected as case of this study. In control group, age, sex match patients of IHD undergoing CAG not having DM were included. Every patient was clinically examined by detailed history and physical examination during entry into study. ECG, chest X-ray, echocardiogram, blood sugar (fasting), blood 2 hrs. after 75gm of glucose and or breakfast were analyzed. Coronary angiography was done in all patients through femoral approach by modified Seldinger technique. Carotid arteriography was performed selective and non­selective method by Hunter head or right Judkin's catheter in standard AP, lateral and oblique views. Results: A total number of 100 patients were included in this study. Of them 50 patients were coronary artery disease with diabetes mellitus and another 50 patients were coronary artery disease without diabetes mellitus. Morphological character of the lesion was also assessed. The mean age was found 57.48 years with 6.04 standard deviation (SD) in DM and 55.64 years with 6.34 standard deviation in NDM group and also 56.56 years with 6.49 standard deviation in the whole study population. The value of unpaired t-test was 0.158 and it was insignificant (p>0.05). The common site of lesion was bifurcation, internal carotid, common carotid and external carotid artery which were 13 cases, 9 cases, 4 cases and 1 case respectively. The individual vessel involvement was 9(18.0%) cases in right, 6(12.0%) cases in left, and 3(6.0%) cases in both in DM group whereas 5 (10.0%) cases in right, 3(6.0%) cases in left, and 1(2.0%) case in both in NDM group. It observed that out of 100 study subjects 10 had complex carotid lesion in DM and 4 in NDM. Concussion: In conclusion the common site of lesion was bifurcation and internal carotid artery mostly in right side. Journal of Current and Advance Medical Research, January 2023;10(1):7-12
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