推进时间拉伸计算细胞成像中的相位恢复

Yueqin Li, Jun Qin, Jian Sun, Min Miao
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引用次数: 0

摘要

时间拉伸成像系统是实现实时成像和低延迟细胞筛选的一种有前途的方法。为便于评估用于细胞检测的时间拉伸成像系统,我们提出了时间拉伸定量相位成像(TS-QPI)系统中的相位恢复模拟器。该模拟器可对 TS-QPI 系统进行高效评估,证明在多种细胞筛选条件下准确恢复相位的可行性,并根据目标细胞的特性设计 TS-QPI 系统。此外,它还能合成模拟相位图像,在训练细胞检测机器学习模型时非常有利于数据扩增。
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Advancing phase recovery in time-stretch computational cell imaging
The time-stretch imaging system is a promising method for achieving real-time imaging and low-latency cell screening. To facilitate the evaluation of time-stretch imaging systems for cell detection, we present a simulator for phase recovery in a time-stretch quantitative phase imaging (TS-QPI) system. The simulator enables the efficient evaluation of TS-QPI system, demonstrating the feasibility of accurate phase recovery for a wide range of cell screening conditions and designing the TS-QPI systems depending on the characteristics of the target cells. Furthermore, it allows synthesis of simulated phase images highly beneficial in data augmentation when training machine learning models for cell detection.
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