某地区癌症医院 Co-60 放射治疗机的深度剂量百分比与已公布数据的比较

Javaid Ali, Muhammd Sohail, Abdul Samad, Israr Ahmad, Hafeezullah Soomro, Ghufran Biradar, Irum Naz, Imadullah Tariq
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摘要

在体外射束放射治疗中,深度剂量百分比(PDD)是估算患者剂量和靶区剂量分布的主要因素,因此准确估算深度剂量百分比非常重要。本文旨在比较巴基斯坦一家地区性癌症医院的钴-60(Co-60)放射治疗机在不同深度和射野大小时沿中心轴的深度剂量百分比与不同作者发表的深度剂量百分比。在 Theratron phoenix Co-60 机器上,使用专用水模型估算不同深度和不同场强的 PDD。据观察,对于 Co-60 射束的 10×10 平方厘米锉刀尺寸,不同作者测量的 PDD 与公布的 PDD 的平均百分比差异为 -0.29% 至 1.13%,在可接受的 ± 2% 范围内。然而,对于一位使用半经验方程计算 PDDs 的作者来说,在 10×10 平方厘米、25×25 平方厘米和 30×30 平方厘米的钴-60 光束场尺寸下,测量的 PDDs 与作者的 PDDs 之间的平均百分比差异分别为 -3.23%、4.69% 和 5.88%,在可接受的 ±10% 范围内。在给定深度下,随着磁场大小的增加,PDDs 也明显增加,这表明二次散射辐射的作用非常明显。此外,测得的 PDD 与大多数作者发表的 PDD(即 ±2%)十分吻合,但在某些磁场尺寸和某些深度,测得的 PDD 与只有一位作者发表的 PDD(即 ±10%)略有吻合,这需要通过获取更多此类数据来纠正。
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Comparison of Percentage Depth Doses with the Published Data for Co-60 Radiotherapy Machine at a Regional Cancer Hospital
In external beam radiation therapy, the percentage depth dose (PDD) is a main factor for estimation of patient’s dose and dose distribution in target volume, therefore its accurate estimation is important. The purpose of this article is to compare PDDs with the published PDDs of different authors along central axis at different depths and field sizes for cobalt-60 (Co-60) radiotherapy machine at a regional cancer hospital Pakistan. A dedicated water phantom was used for estimation of PDDs at different depths and different field sizes, for Theratron phoenix Co-60 machine. It was observed that for 10×10 cm2 filed size of Co-60 beam mean percent variation in measured PDDs and published PDDs by different authors was -0.29% to 1.13%, which was within acceptable limit of ± 2%. However, for one author who used semi-empirical equation for PDDs calculation, the mean percent variation between measured PDDs and that of the author was -3.23%, 4.69% and 5.88% for 10×10 cm2, 25×25 cm2 and 30×30 cm2 field sizes of Co-60 beam respectively, which were within acceptable limit of   ±10%. A noticeable increase in PDDs was observed with increase of the field size at given depth which shows obvious contribution of secondary scattered radiation. Also measured PDDs were well matched with that of published PDDs of most of the authors i.e. ± 2%, but the measured PDDs were moderately matched with that of PDDs for only one author for some field sizes and some depths i.e. ±10%, which need to be rectified by taking more such data.
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