成人颅咽管瘤:病例报告

Avtar S. Dhanju, Nisha Narang, Manavdeep Kaur, Rishabh Rikhye, Pankaj Jassal, Adab Alwinder Singh
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摘要

我们讨论的是一例 70 岁男性颅咽管瘤患者的病例报告。患者主诉发高烧,感觉改变,出现脑膜刺激征和眼底检查乳头水肿。脑部三维核磁共振成像(MRI 3D)显示,小脑上部有细长的分叶状肿块病变。该病多发于20岁以前的年轻人,以头痛、喷射状呕吐和颅内压升高为特征,但也有可能发生在老年人群中。它起源于颅咽管或拉斯克囊的胚胎鳞状上皮残余。它发育在下丘脑附近,靠近控制生长和许多身体功能的垂体。通常情况下,它们是良性的,但有时也可能是恶性的,因为它们会干扰神经内分泌结构或引起神经心理并发症,从而导致严重问题。全世界只有少数老年患者患有颅咽管瘤。
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Craniopharyngioma in adults: a case report
We are discussing a case report of 70-year-old male patient with craniopharyngioma who presented with complaint of high grade fever and altered sensorium with presence of meningeal irritation signs and papilledema in fundus examination. MRI 3D brain showed elongated lobulated mass lesion in the suprasellar region. It mostly occurs in young age before 20 years of age with features of headache, projectile vomiting and signs of raised intracranial pressure but there is possibility of its occurrence in older age group. It arises from embryologic squamous epithelial remnants of the craniopharyngeal duct or Rathke’s pouch. It develops near the hypothalamus near the pituitary gland that controls growth and many body functions. Usually, they are benign but can be malignant sometimes as they can cause serious problems by interfering with neuroendocrine structures or neuropsychological complications. There are only few cases of craniopharyngioma in old age patients worldwide.
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