经皮硬化剂注射治疗良性血管病变:回顾性研究

O. Panta, Abhishek Adhikari, Babin Basnet, B. Pantha, Ram Kumar Ghimire
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引用次数: 0

摘要

导言:硬化剂注射疗法是一种微创方法,作为治疗这些病变的一种治疗方式,它的地位日益突出。本文旨在评估硬化疗法的临床成功率、并发症和围手术期疼痛评分,以及它们随病变性质和硬化剂选择而产生的变化。研究方法这是一项基于医院病历的回顾性研究,研究对象是加德满都的一家三级医疗中心。对 2019 年 1 月至 2022 年 12 月期间在该中心进行的硬化剂治疗的病变性质、临床成功率、治疗次数、围术期疼痛评分和并发症进行了评估。所有硬化疗法均在介入放射科医生的USG和透视联合引导下进行。数据输入预先设计的表格,并使用 SPSS 25.0 进行数据分析。结果研究期间,共有 33 名患者接受了 61 次硬化剂注射治疗。静脉畸形(72.2%)是最常见的血管病变,其次是血管瘤。硬化疗法后症状明显缓解的病例占 95%,完全消肿的病例占 65.38%,部分消肿且外观效果可接受的病例占 26.92%。只有 6.5% 的病例出现了轻微并发症。围手术期疼痛的中位数为 5 分,四分位间范围为 2 分。使用十四烷基硫酸钠的围手术期疼痛明显少于酒精(P-0.002)。血管瘤肿胀的缓解程度低于其他病变,而所有病变的疼痛缓解程度相似。只有酒精组出现了并发症。结论:硬化疗法是一种安全有效的良性血管病变治疗方法。与酒精相比,使用十四烷基硫酸钠的并发症和围手术期疼痛较少。
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Percutaneous Sclerotherapy as Therapeutic Option in Benign Vascular Lesions: A Retrospective Study
Introduction:Sclerotherapy, a minimally invasive approach, has gained prominence as a therapeutic modality for the treatment of these lesions. The objective of this article is to assess clinical success, complications and periprocedural pain score of sclerotherapy and their variation with the nature of the lesion and choice of sclerosants. Methods: This was a hospital record-based retrospective study in a tertiary care centre in Kathmandu. Sclerotherapy done in the institute from January 2019 to December 2022 was evaluated for the nature of the lesion, clinical success, number of sessions, periprocedural pain score and complications. All sclerotherapy was performed under combined USG and fluoroscopic guidance by an interventional radiologist. Data was entered in predesigned proforma and data analysis was done using SPSS 25.0. Results: A total of 33 patients underwent 61 sessions of sclerotherapy during the study period. Venous malformation (72.2%) was the most common vascular lesion followed by hemangioma. There was significant resolution of symptoms post sclerotherapy pain relief in 95% complete resolution of swelling in 65.38 % and partial resolution with acceptable cosmetic results in 26.92% of cases. Only minor complications were seen in 6.5% of cases. The median periprocedural pain score was 5 with an interquartile range of 2. Periprocedural pain was significantly less with sodium tetradecyl sulphate than with alcohol(P-0.002). The resolution of swelling was less in hemangiomas than in other lesions, while pain relief was similar for all lesions. Complications were seen only in the alcohol group. Conclusions: Sclerotherapy is a safe and effective procedure for benign vascular lesions. Complications and periprocedural pain are less with sodium tetradecyl sulphate as compared to alcohol.
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