顺铂- mecy作为晚期卵巢癌复发的补救性化疗。

Giornale italiano di oncologia Pub Date : 1989-01-01
M Belli, G Colantuoni, B Di Iorio
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引用次数: 0

摘要

顺铂(DDP)已被证明在卵巢腺癌的治疗中具有很高的活性。作者用一种交替方案治疗了12例组织学证实的晚期卵巢癌患者,交替方案包括每周4个DDP疗程(1mg /kg体重/周),然后每月疗程高剂量甲氨蝶呤(750mg /mq静脉注射)加环磷酰胺(250mg /mq静脉注射5天)(Mecy)。DDP + Mecy交替方案被证明作为晚期卵巢癌患者的拯救性化疗方案具有显著的活性。
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Cis-platin-Mecy as salvage chemotherapy in recurrent advanced ovarian carcinoma.

Cis-platin (DDP) has proved to be highly active in the treatment of ovarian adenocarcinoma. The Authors have treated 12 patients with istologically proven advanced ovarian carcinoma with a type of alternating regimen consisting of four weekly DDP courses (1 mg/kg b.w./week) followed by monthly courses high-dose methotrexate (750 mg/mq i.v.) plus cyclophosphamide (250 mg/mq for 5 days) (Mecy). The alternating regimen DDP + Mecy proved to have significant activity as a salvace chemiotherapy regimen for patients with advanced ovarian carcinoma.

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