绝经前后妇女的血脂异常:对城市周边 Paundra 刹帝利妇女的研究

D. K. Adak, Nitamoni Bharali, Saptarshi Biswas, N. Bagchi, Tapas Kumar Biswas, Vadlamudi Raghavendra Rao
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摘要

血脂异常是心血管疾病的一个重要危险因素,而绝经是指妇女育龄期结束时卵巢卵泡活动减少,绝经带来的激素变化对血清脂质的影响很大。本研究针对印度西孟加拉邦南 24 Parganas 的 Sonarpur 地区绝经前后的 Paundra 刹帝利妇女开展,以确定血脂异常的患病率。研究人员从西孟加拉邦南24帕尔干纳斯省索纳尔布尔的近郊区选取了142名成年刹帝利妇女(绝经前妇女96人,绝经后妇女46人)。记录了人体测量和动脉压数据。研究人员采集了空腹 12 小时的血液样本。19.79%的绝经前妇女和 17.39%的绝经后妇女血脂水平正常。与绝经前妇女(80.2%)相比,绝经后妇女的血脂异常患病率略高(82.7%)。在绝经前妇女中,高低密度脂蛋白胆固醇是导致血脂异常的主要原因之一,而在绝经后妇女中,高胆固醇血症则是导致血脂异常的主要原因之一。回归分析表明,3 个因素对绝经前妇女有重大影响,6 个因素对绝经后妇女有重大影响。虽然保德拉刹帝利妇女保持着相对较少压力和高运动量的生活方式,但她们的血脂异常水平很高。由于靠近城市中心加尔各答,城郊人口的生活方式和饮食习惯正在发生变化。 资助单位:印度政府文化部印度人类学调查所
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Dyslipidemia in pre- and post-menopausal women: a study of peri-urban Paundra Kshatriya women
Dyslipidemia is an important risk factor of cardiovascular disease, whereas menopause is a decrease in ovarian follicular activity at the end of reproductive age of the women, which is significantly influenced by hormonal changes brought on by menopause’s impact on serum lipids. This study was undertaken among pre- and post-menopausal Paundra Kshatriya women in Sonarpur, South 24 Parganas, West Bengal, India in order to determine the prevalence of dyslipidemia. 142 adult Paundra Kshatriya women (n pre-menopausal women = 96; n post-menopausal women = 46) were selected from a peri-urban setting of Sonarpur, South 24 Parganas, West Bengal. Anthropometry and arterial pressure data were recorded. Blood samples were collected from study participants who were on 12 hours fasting. 19.79% of pre-menopausal women and 17.39% of post-menopausal women had normal levels of lipids. Prevalence of dyslipidemia was slightly higher (82.7%) among the post-menopausal women compared to pre-menopausal women (80.2%). While high LDL cholesterol emerged as one of the prime causes for dyslipidemia among pre-menopausal women, hypercholesterolemia emerged as one of the prime causes for dyslipidemia among post-menopausal women. Regression analysis revealed a significant impact of 3 factors in pre-menopausal women and impact of 6 factors in post-menopausal women. Though Paundra Kshatriya women maintain a relatively less stressful and high physical activity lifestyle, they exhibited high levels of lipid abnormalities. The peri-urban population is undergoing lifestyle and dietary changes due to a close proximity to the urban centre, Kolkata.   Funding Anthropological Survey of India, Ministry of Culture, Government of India
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