急性环形心肌梗死复杂血管状态患者重复溶栓治疗的病例报告

D. V. Bosikov, N. V. Stepanova, V. E. Tarasova, Yu.  M. Botnar
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引用次数: 0

摘要

本临床病例报告显示,49 岁的急性环心尖心肌梗死患者在接受了一次全身溶栓治疗 rtPA 无效后,采用了非标准方法重复溶栓治疗。此外,对于机械性再灌注明显延迟的病例,在医院阶段重复溶栓治疗是至关重要的选择。在引入rtPA 90分钟后,我们的心电图出现了阴性动态变化,即其他(早期完整)导联出现额外的ST段抬高,并再次出现标准剂量麻醉镇痛药无法缓解的血管性疼痛。在偏远的PCI中心,我们认为机械性再灌注会造成严重的心肌梗死。考虑到这些因素,即发生意外情况的高风险和难治性血管疼痛,我们决定再次使用非免疫原性葡萄球菌酶进行溶栓治疗,疗效显著。后来,病情逐渐恢复正常。
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Case report of repeat thrombolytic therapy in patient with acute circular-apical myocardial infarction, complicated anginous status
Presented clinical case report illustrates nonstandart approach use repeat thrombolytic therapy patient 49 y.o. with acute circular – apical myocardial infarction, after noneffective primary systemic thrombolytic therapy rtPA. Moreover, repeat thrombolytic therapy in hospital stage was vital alternative in case with significant tamely delay mechanical reperfusion. After 90 minutes then introduction rtPA has been done, we got negative dynamic on ECG in the form of additional ST-segment elevation at other (early intact) lead, and reccurent anginous pain refractory to standard doses narcotic analgesic. In connection with remote PCI – center, we supposed significant tamely deIlay to mechanical reperfusion. In view of this factors, high risk to undesired event, refractory anginous pain, we made decision of repeat thrombolytic therapy with non-immunogenic staphilokinase, and it has been effective. At a later time the disease is taking it’s normal course.
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