Higher Chinese Healthy Eating Index Scores are Associated with a Lower Risk of Hyperuricemia: A Large Cross-Sectional Survey Based in China

Hyperuricemia (HUA) is a metabolic disease with an increasing prevalence in China and worldwide. Few studies have focused on the relationship between daily dietary quality and hyperuricemia in China. Data were obtained from the China Health and Nutrition Survey (CHNS). Adults with complete dietary survey and uric acid data were selected for the study, along with complete data on covariates about demographics, lifestyle, and history of disease. The Chinese Healthy Eating Index (CHEI) was used to reflect the quality of daily diet. The logistic regression model and weighted quantile sum (WQS) regression model were used to explore the relationship between CHEI score and risk of HUA. WQS regression models can also further assess the contribution of the various dietary components of CHEI in reducing the risk of HUA. There was a not-significant trend in protective effect between higher CHEI scores and HUA risk in the logistic regression model. In the WQS model, higher CHEI scores showed a significant protective effect on the HUA (OR: .601,0.298-.907). Fruits, tubers, and dairy were top contributor in the protective effect of CHEI (26.81%, 14.34%, and 12.95%, respectively). Higher CHEI associated with lower HUA risk in Chinese adults, and more attention should be paid to fruits, tubers, and dairy.