阴茎癌患者罕见股骨干骨转移的早期发现病例报告

Kumar Yadav Ajay, Kumar Mandal Sandip, Gnawali Suman, Dutta Adhikari Ganga, Sharma Nitu, Shailesh Kumar Pandey, Deepika Dhakal, Pandit Anil
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引用次数: 0

摘要

背景。骨转移在许多癌症的晚期阶段非常常见。在阴茎癌中,淋巴结转移在某种程度上很常见,但继发于阴茎癌的淋巴结转移报告却非常罕见。在此,我们介绍了一名患有阴茎鳞状细胞癌的 51 岁尼泊尔男性患者。患者的计算机断层扫描(ct)显示,癌细胞累及龟头阴茎,并伴有双侧腹股沟内外淋巴结病。随后,患者接受了阴茎部分切除术和双侧腹股沟淋巴结切除术,并完成了 6 个周期的化疗。治疗一年后,患者出现大腿疼痛和头痛,医生建议他进行脑部磁共振成像(mRi)、99m锝-MDP全身骨扫描以及骨盆和大腿ct扫描。检查报告显示,颅骨顶端出现硬化性改变,右股骨近端颈部下方出现中度 99mTc-MDP 摄取,d/d 转移。从股骨病变处提取的真切活检组织病理学检查显示为转移性角化鳞状细胞癌,这是阴茎癌继发股骨干骨转移的罕见病例。随后,患者被送去进行股骨重建手术。根据病例研究回顾,阴茎癌引起的股骨干骨转移极为罕见。据我们所知,这是第一例早期发现股骨干骨转移的阴茎癌患者。早期诊断有助于根治性治疗和姑息治疗。手术是治疗的首选方案,尤其是对于长骨转移灶。
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A case report of early detection of rare femoral shaft bone metastasis in a penis cancer patient
Background. Bone metastasis is very common in the advanced stage of numerous carcinomas. In penile carcinoma, lymph nodes metastasis is somehow common but it is very rare reported to be secondary from penile cancer. till the date, there are only few cases of penis carcinoma reported bone metastasis in literature worldwide.Case Presentation. Herein, We presented a 51-year-old Nepalese male with squamous cell carcinoma of penis. computed tomography (ct) scan of the patient revealed that there was carcinoma involving glans penis and precure with bilateral external & internal inguinal lymphadenopathies. After then, the patient was under gone for partial penectomy and bilateral inguinal lymphadenectomy and complete 6-cycle chemotherapy. After one year of treatment, patient developed thigh pain and headache and he advised to have magnetic Resonance imaging (mRi) of brain, 99mTc-MDP whole body bone scan and ct scan of pelvis and thigh. The examination report reveals that there was a sclerotic change in vertex of skull bone and moderate 99mTc-MDP uptake in right proximal shaft of femur just below the neck d/d metastasis. The histopathological examination of the true cut biopsy taken from the lesion of the femur showed metastatic keratinizing squamous cell carcinoma which is rare case of femoral shaft bone metastasis secondary from penile carcinoma. Then patient was sent for surgical reconstruction of femur. Based on the case studies review femur shaft bone metastasis from penile cancer is extremely rare.Conclusion. The best of our knowledge; this is the first early detected bone metastases to shaft of the femur in a patient with penile cancer. early diagnosis helps to radical treatment as well as palliative treatment. surgery is the preferred option of the treatments, especially for metastatic foci in the long bones.
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来源期刊
Siberian journal of oncology
Siberian journal of oncology Medicine-Oncology
CiteScore
0.40
自引率
0.00%
发文量
117
审稿时长
8 weeks
期刊介绍: The main objectives of the journal are: -to promote the establishment of Russia’s leading worldwide positions in the field of experimental and clinical oncology- to create the international discussion platform intended to cover all aspects of basic and clinical cancer research, including carcinogenesis, molecular biology, epidemiology, cancer prevention, diagnosis and multimodality treatment (surgery, chemotherapy, radiation therapy, hormone therapy), anesthetic management, medical and social rehabilitation, palliative care as well as the improvement of life quality of cancer patients- to encourage promising young scientists to be actively involved in cancer research programs- to provide a platform for researches and doctors all over the world to promote, share, and discuss various new issues and developments in cancer related problems. (to create a communication platform for the expansion of cooperation between Russian and foreign professional associations).- to provide the information about the latest worldwide achievements in different fields of oncology The most important tasks of the journal are: -to encourage scientists to publish their research results- to offer a forum for active discussion on topics of major interest - to invite the most prominent Russian and foreign authors to share their latest research findings with cancer research community- to promote the exchange of research information, clinical experience, current trends and the recent developments in the field of oncology as well as to review interesting cases encountered by colleagues all over the world- to expand the editorial board and reviewers with the involvement of well-known Russian and foreign experts- to provide open access to full text articles- to include the journal into the international database- to increase the journal’s impact factor- to promote the journal to the International and Russian markets
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