膀胱尿路上皮癌的基质骨化:一个不寻常且具有挑战性的特征。病例报告

Irene Iglesias de Ussel Galarreta, Francisco Javier Queipo Gutiérrez
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引用次数: 0

摘要

一名 62 岁的男性在 3 个月前开始出现疼痛和血尿。计算机断层扫描显示膀胱局灶和壁层增厚,输尿管肾盂扩张。随后的经尿道膀胱切除术发现了高级别肌层浸润性尿路上皮癌。在随后的膀胱前列腺切除术中,我们发现了同样的肿瘤,但增加了与肿瘤相关的灶性基质骨化变。骨化变是尿路上皮癌中极为罕见的特征,仅有少数病例报道,是诊断上的一个难题,会模仿放疗诱发的肉瘤或肉瘤样癌。
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Stromal osseous metaplasia in urothelial carcinoma of the bladder: An unusual and challenging feature. A case report

A 62-year-old male presented with pain and haematuria starting 3 months before. The computed tomography showed focal and mural bladder thickening with ureteropelvic dilatation. The following transurethral bladder resection revealed a high-grade muscle-invasive urothelial carcinoma. In the subsequent cystoprostatectomy we found the same tumour, but adding focal tumour-associated stromal osseous metaplasia.

Ossifying metaplasia is an extremely rare feature in urothelial carcinoma, with a few reported cases and represents a diagnostic challenge, mimicking radiotherapy-induced sarcoma or sarcomatoid carcinoma.

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来源期刊
Revista Espanola de Patologia
Revista Espanola de Patologia Medicine-Pathology and Forensic Medicine
CiteScore
0.90
自引率
0.00%
发文量
53
审稿时长
34 days
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