Survival Evaluation in Patients Over 70 Years of Age With Advanced Stage Non-small Cell Lung Cancer

Objectives: Non-small cell lung (NSCLC) cancer is usually seen in elderly patients. The impact of over 70 age on the survival of patients with NSCLC has not been studied. This study aimed to evaluate the impact of demographic and clinical variables on survival in Stage IV the NSCLC elderly patient. Methods: This study was a retrospective cohort analysis of 244 patients with advanced stage NSCLC, between January 2015 and December 2019. The patients were classified as the <70 years and ≥70 years. The primary and secondary outcomes were the overall survival and the impact of the demographics and clinical variables on survival, respectively. Results: The numbers of patients who were <70 and ≥70 years were 136 (55.7%) and 108 (44.3%), respectively. Although the overall survival in patients aged 70 years or older was shorter than that of the younger patients, the difference was statistically insignificant (p=0.236). Weight loss, ≥2 comorbidities and TNM stage IV were significantly associated with shorter overall survival. Conclusion: Weight loss, increased comorbidities and TNM stage IV are the independent risk factors for overall survival in patients with advanced stage of NSCLC. Older age did not found any impact on survival in the study.